Lack of effect of chlorhexidine varnish on Streptococcus mutans transmission and caries in mothers and children

Ananda Dasanayake, H. W. Wiener, Yihong Li, S. V. Vermund, P. W. Caufield

Research output: Contribution to journalArticle

Abstract

In a randomized clinical trial, we evaluated the effect of a 10% chlorhexidine varnish (Chlorzoin®) on the mother-child transmission of Streptococcus mutans and on subsequent caries experience. Chlorhexidine (n = 38) or a placebo varnish (n = 37) was applied to the dentitions of 75 mothers at a time when their first babies were about 6 months old (approximate time of first tooth emergence). Three more applications at weekly intervals and subsequent applications at 6-month intervals followed the initial application. The mother-child pairs were followed up until the child's fourth birthday. Maternal salivary S. mutans levels in the treatment group remained significantly lower (p < 0.05) compared to the control group up to 12 months after the initial application. However, this intervention did not significantly alter the S. mutans colonization in children or the caries increment in either the mother or the child.

Original languageEnglish (US)
Pages (from-to)288-293
Number of pages6
JournalCaries Research
Volume36
Issue number4
StatePublished - Jul 2002

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Chlorhexidine
Streptococcus mutans
Paint
Mothers
Dentition
Tooth
Randomized Controlled Trials
Placebos
Control Groups

Keywords

  • Chlorhexidine
  • Randomized clinical trial
  • Streptococcus mutans
  • Transmission

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Lack of effect of chlorhexidine varnish on Streptococcus mutans transmission and caries in mothers and children. / Dasanayake, Ananda; Wiener, H. W.; Li, Yihong; Vermund, S. V.; Caufield, P. W.

In: Caries Research, Vol. 36, No. 4, 07.2002, p. 288-293.

Research output: Contribution to journalArticle

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