Label-free microscale thermophoresis discriminates sites and affinity of protein-ligand binding

Susanne A I Seidel, Christoph J. Wienken, Sandra Geissler, Moran Jerabek-Willemsen, Stefan Duhr, Alwin Reiter, Dirk Trauner, Dieter Braun, Philipp Baaske

Research output: Contribution to journalArticle

Original languageEnglish (US)
Pages (from-to)10656-10659
Number of pages4
JournalAngewandte Chemie - International Edition
Volume51
Issue number42
DOIs
StatePublished - Oct 15 2012

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Thermophoresis
Protein Conformation
Microfluidics
Protein Stability
Binding sites
Thermodynamics
Protein Binding
Labels
Binding Sites
Ligands
Proteins

Keywords

  • analytical methods
  • binding affinity
  • label-free methods
  • microscale thermophoresis
  • protein conformation

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis

Cite this

Seidel, S. A. I., Wienken, C. J., Geissler, S., Jerabek-Willemsen, M., Duhr, S., Reiter, A., ... Baaske, P. (2012). Label-free microscale thermophoresis discriminates sites and affinity of protein-ligand binding. Angewandte Chemie - International Edition, 51(42), 10656-10659. https://doi.org/10.1002/anie.201204268

Label-free microscale thermophoresis discriminates sites and affinity of protein-ligand binding. / Seidel, Susanne A I; Wienken, Christoph J.; Geissler, Sandra; Jerabek-Willemsen, Moran; Duhr, Stefan; Reiter, Alwin; Trauner, Dirk; Braun, Dieter; Baaske, Philipp.

In: Angewandte Chemie - International Edition, Vol. 51, No. 42, 15.10.2012, p. 10656-10659.

Research output: Contribution to journalArticle

Seidel, SAI, Wienken, CJ, Geissler, S, Jerabek-Willemsen, M, Duhr, S, Reiter, A, Trauner, D, Braun, D & Baaske, P 2012, 'Label-free microscale thermophoresis discriminates sites and affinity of protein-ligand binding', Angewandte Chemie - International Edition, vol. 51, no. 42, pp. 10656-10659. https://doi.org/10.1002/anie.201204268
Seidel SAI, Wienken CJ, Geissler S, Jerabek-Willemsen M, Duhr S, Reiter A et al. Label-free microscale thermophoresis discriminates sites and affinity of protein-ligand binding. Angewandte Chemie - International Edition. 2012 Oct 15;51(42):10656-10659. https://doi.org/10.1002/anie.201204268
Seidel, Susanne A I ; Wienken, Christoph J. ; Geissler, Sandra ; Jerabek-Willemsen, Moran ; Duhr, Stefan ; Reiter, Alwin ; Trauner, Dirk ; Braun, Dieter ; Baaske, Philipp. / Label-free microscale thermophoresis discriminates sites and affinity of protein-ligand binding. In: Angewandte Chemie - International Edition. 2012 ; Vol. 51, No. 42. pp. 10656-10659.
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