Abstract
Kolente virus (KOLEV) is a rhabdovirus originally isolated from ticks and a bat in Guinea, West Africa, in 1985. Although tests at the time of isolation suggested that KOLEV is a novel rhabdovirus, it has remained largely uncharacterized. We assembled the complete genome sequence of the prototype strain DakAr K7292, which was found to encode the five canonical rhabdovirus structural proteins (N, P, M, G and L) with alternative ORFs (.180 nt) in the P and L genes. Serologically, KOLEV exhibited a weak antigenic relationship with Barur and Fukuoka viruses in the Kern Canyon group. Phylogenetic analysis revealed that KOLEV represents a distinct and divergent lineage that shows no clear relationship to any rhabdovirus except Oita virus, although with limited phylogenetic resolution. In summary, KOLEV represents a novel species in the family Rhabdoviridae.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2609-2615 |
| Number of pages | 7 |
| Journal | Journal of General Virology |
| Volume | 94 |
| Issue number | PART 12 |
| DOIs | |
| State | Published - Dec 2013 |
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ASJC Scopus subject areas
- Virology
Cite this
Kolente virus, a rhabdovirus species isolated from ticks and bats in the Republic of Guinea. / Ghedin, Elodie; Rogers, Matthew B.; Widen, Steven G.; Guzman, Hilda; da Rosa, Amelia P A Travassos; Wood, Thomas G.; Fitch, Adam; Popov, Vsevolod; Holmes, Edward C.; Walker, Peter J.; Vasilakis, Nikos; Tesh, Robert B.
In: Journal of General Virology, Vol. 94, No. PART 12, 12.2013, p. 2609-2615.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Kolente virus, a rhabdovirus species isolated from ticks and bats in the Republic of Guinea
AU - Ghedin, Elodie
AU - Rogers, Matthew B.
AU - Widen, Steven G.
AU - Guzman, Hilda
AU - da Rosa, Amelia P A Travassos
AU - Wood, Thomas G.
AU - Fitch, Adam
AU - Popov, Vsevolod
AU - Holmes, Edward C.
AU - Walker, Peter J.
AU - Vasilakis, Nikos
AU - Tesh, Robert B.
PY - 2013/12
Y1 - 2013/12
N2 - Kolente virus (KOLEV) is a rhabdovirus originally isolated from ticks and a bat in Guinea, West Africa, in 1985. Although tests at the time of isolation suggested that KOLEV is a novel rhabdovirus, it has remained largely uncharacterized. We assembled the complete genome sequence of the prototype strain DakAr K7292, which was found to encode the five canonical rhabdovirus structural proteins (N, P, M, G and L) with alternative ORFs (.180 nt) in the P and L genes. Serologically, KOLEV exhibited a weak antigenic relationship with Barur and Fukuoka viruses in the Kern Canyon group. Phylogenetic analysis revealed that KOLEV represents a distinct and divergent lineage that shows no clear relationship to any rhabdovirus except Oita virus, although with limited phylogenetic resolution. In summary, KOLEV represents a novel species in the family Rhabdoviridae.
AB - Kolente virus (KOLEV) is a rhabdovirus originally isolated from ticks and a bat in Guinea, West Africa, in 1985. Although tests at the time of isolation suggested that KOLEV is a novel rhabdovirus, it has remained largely uncharacterized. We assembled the complete genome sequence of the prototype strain DakAr K7292, which was found to encode the five canonical rhabdovirus structural proteins (N, P, M, G and L) with alternative ORFs (.180 nt) in the P and L genes. Serologically, KOLEV exhibited a weak antigenic relationship with Barur and Fukuoka viruses in the Kern Canyon group. Phylogenetic analysis revealed that KOLEV represents a distinct and divergent lineage that shows no clear relationship to any rhabdovirus except Oita virus, although with limited phylogenetic resolution. In summary, KOLEV represents a novel species in the family Rhabdoviridae.
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U2 - 10.1099/vir.0.055939-0
DO - 10.1099/vir.0.055939-0
M3 - Article
VL - 94
SP - 2609
EP - 2615
JO - Journal of General Virology
JF - Journal of General Virology
SN - 0022-1317
IS - PART 12
ER -