Intraoral effects of a fluoride-releasing device on acid-softened enamel.

R. E. Corpron, J. W. Clark, A. Tsai, Frederick More, D. F. Merrill, C. J. Kowalski, T. R. Tice, C. E. Rowe

Research output: Contribution to journalArticle

Abstract

Among the anticaries benefits of fluorides is the remineralization of incipient carious lesions. There is increasingly convincing evidence that low-potency fluoride agents applied frequently are effective in remineralizing early carious lesions. This study of in vivo remineralization used an intraoral appliance with demineralized enamel slabs mounted in the appliance and an innovative method of fluoride delivery, the fluoride-releasing device, which releases a controlled amount of fluoride (0.3 mg fluoride every 24 hours) on exposure to saliva. After control and treatment periods of 7 and 30 days, the enamel specimens were removed from the appliance and evaluated for microhardness, acid resistance, and fluoride uptake. The treated specimens significantly exceeded the values of their corresponding controls in all parameters measured, indicating that considerable remineralization of the treated enamel had occurred at both 7 and 30 days. Although the longer period of treatment produced greater results, considerable effects were observed after 7 days. This model system provided for an in vivo environment to study the effects of treatment of the FRD and allowed for subsequent recovery of the enamel specimens for evaluation. The results of this study are encouraging with respect to the efficacy of a fluoride-releasing device but indicate that subsequent clinical testing of the effects of FRDs on incipient carious lesions in the natural dentition of human subjects is necessary.

Original languageEnglish (US)
Pages (from-to)383-388
Number of pages6
JournalJournal of the American Dental Association
Volume113
Issue number3
StatePublished - Sep 1986

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Dental Enamel
Fluorides
Equipment and Supplies
Acids
Dentition
Saliva

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Corpron, R. E., Clark, J. W., Tsai, A., More, F., Merrill, D. F., Kowalski, C. J., ... Rowe, C. E. (1986). Intraoral effects of a fluoride-releasing device on acid-softened enamel. Journal of the American Dental Association, 113(3), 383-388.

Intraoral effects of a fluoride-releasing device on acid-softened enamel. / Corpron, R. E.; Clark, J. W.; Tsai, A.; More, Frederick; Merrill, D. F.; Kowalski, C. J.; Tice, T. R.; Rowe, C. E.

In: Journal of the American Dental Association, Vol. 113, No. 3, 09.1986, p. 383-388.

Research output: Contribution to journalArticle

Corpron, RE, Clark, JW, Tsai, A, More, F, Merrill, DF, Kowalski, CJ, Tice, TR & Rowe, CE 1986, 'Intraoral effects of a fluoride-releasing device on acid-softened enamel.', Journal of the American Dental Association, vol. 113, no. 3, pp. 383-388.
Corpron RE, Clark JW, Tsai A, More F, Merrill DF, Kowalski CJ et al. Intraoral effects of a fluoride-releasing device on acid-softened enamel. Journal of the American Dental Association. 1986 Sep;113(3):383-388.
Corpron, R. E. ; Clark, J. W. ; Tsai, A. ; More, Frederick ; Merrill, D. F. ; Kowalski, C. J. ; Tice, T. R. ; Rowe, C. E. / Intraoral effects of a fluoride-releasing device on acid-softened enamel. In: Journal of the American Dental Association. 1986 ; Vol. 113, No. 3. pp. 383-388.
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