Intramolecular vinyl quinone Diels-Alder reactions: Asymmetric entry to the cordiachrome core and synthesis of (-)-isoglaziovianol

Florian Löbermann, Lara Weisheit, Dirk Trauner

Research output: Contribution to journalArticle

Abstract

A short and asymmetric entry to the core structure of the cordiachromes has been developed, allowing access to (-)-isoglaziovianol in seven steps. Our synthesis includes a Trost asymmetric allylic alkylation and a reaction cascade triggered by a vinyl quinone Diels-Alder reaction and followed by intramolecular nucleophilic interception.

Original languageEnglish (US)
Pages (from-to)4324-4326
Number of pages3
JournalOrganic Letters
Volume15
Issue number17
DOIs
StatePublished - Sep 6 2013

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ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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