Intermolecular interactions in sodium deoxycholate micelles: An NMR study involving a spin-labeled cholestane

Gennaro Esposito, A. Zanobi, E. Giglio, N. V. Pavel, I. D. Campbell

Research output: Contribution to journalArticle

Abstract

A 1H and 13C NMR study of the interaction between sodium deoxycholate (NaDC) micelles and a nitroxide probe (cholestane spin-label, CSL) is presented. It is shown that CSL primarily interacts with the β face of NaDC. The 1H NMR relaxation data enable the spatial geometry of the interaction to be defined. van der Waals energy calculations show that the CSL-NaDC interaction corresponds to a minimum if a helical model, previously proposed, is assumed for the NaDC micelle. At high concentrations of CSL, the CSL-NaDC interaction changes and the α face of NaDC may also become involved in the interaction.

Original languageEnglish (US)
Pages (from-to)83-89
Number of pages7
JournalJournal of Physical Chemistry
Volume91
Issue number1
DOIs
StatePublished - Jan 1 1987

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Cholestanes
Spin Labels
Deoxycholic Acid
Micelles
Labels
micelles
Sodium
Nuclear magnetic resonance
sodium
nuclear magnetic resonance
interactions
Geometry
probes
geometry

ASJC Scopus subject areas

  • Engineering(all)
  • Physical and Theoretical Chemistry

Cite this

Intermolecular interactions in sodium deoxycholate micelles : An NMR study involving a spin-labeled cholestane. / Esposito, Gennaro; Zanobi, A.; Giglio, E.; Pavel, N. V.; Campbell, I. D.

In: Journal of Physical Chemistry, Vol. 91, No. 1, 01.01.1987, p. 83-89.

Research output: Contribution to journalArticle

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