Integrated circuits and electrode interfaces for noninvasive physiological monitoring

Sohmyung Ha, Chul Kim, Yu M. Chi, Abraham Akinin, Christoph Maier, Akinori Ueno, Gert Cauwenberghs

    Research output: Contribution to journalArticle

    Abstract

    This paper presents an overview of the fundamentals and state of the-art in noninvasive physiological monitoring instrumentation with a focus on electrode and optrode interfaces to the body, and micropower-integrated circuit design for unobtrusive wearable applications. Since the electrode/optrode-body interface is a performance limiting factor in noninvasive monitoring systems, practical interface configurations are offered for biopotential acquisition, electrode-tissue impedance measurement, and optical biosignal sensing. A systematic approach to instrumentation amplifier (IA) design using CMOS transistors operating in weak inversion is shown to offer high energy and noise efficiency. Practical methodologies to obviate 1/f noise, counteract electrode offset drift, improve common-mode rejection ratio, and obtain subhertz high-pass cutoff are illustrated with a survey of the state-of-the-art IAs. Furthermore, fundamental principles and state-of-the-art technologies for electrode-tissue impedance measurement, photoplethysmography, functional near-infrared spectroscopy, and signal coding and quantization are reviewed, with additional guidelines for overall power management including wireless transmission. Examples are presented of practical dry-contact and noncontact cardiac, respiratory, muscle and brain monitoring systems, and their clinical applications.

    Original languageEnglish (US)
    Article number6748876
    Pages (from-to)1522-1537
    Number of pages16
    JournalIEEE Transactions on Biomedical Engineering
    Volume61
    Issue number5
    DOIs
    StatePublished - Jan 1 2014

    Fingerprint

    Integrated circuits
    Electrodes
    Monitoring
    Photoplethysmography
    Tissue
    Near infrared spectroscopy
    Muscle
    Brain
    Transistors

    Keywords

    • Biological signal sensing
    • biomedical electronics
    • body-electrode interface
    • electrode contacts
    • electrode-tissue impedance
    • functional near-infrared spectroscopy
    • health monitoring
    • instrumentation amplifier (IA)
    • optrode interface
    • photoplethysmography
    • sensor interface

    ASJC Scopus subject areas

    • Biomedical Engineering

    Cite this

    Ha, S., Kim, C., Chi, Y. M., Akinin, A., Maier, C., Ueno, A., & Cauwenberghs, G. (2014). Integrated circuits and electrode interfaces for noninvasive physiological monitoring. IEEE Transactions on Biomedical Engineering, 61(5), 1522-1537. [6748876]. https://doi.org/10.1109/TBME.2014.2308552

    Integrated circuits and electrode interfaces for noninvasive physiological monitoring. / Ha, Sohmyung; Kim, Chul; Chi, Yu M.; Akinin, Abraham; Maier, Christoph; Ueno, Akinori; Cauwenberghs, Gert.

    In: IEEE Transactions on Biomedical Engineering, Vol. 61, No. 5, 6748876, 01.01.2014, p. 1522-1537.

    Research output: Contribution to journalArticle

    Ha, S, Kim, C, Chi, YM, Akinin, A, Maier, C, Ueno, A & Cauwenberghs, G 2014, 'Integrated circuits and electrode interfaces for noninvasive physiological monitoring', IEEE Transactions on Biomedical Engineering, vol. 61, no. 5, 6748876, pp. 1522-1537. https://doi.org/10.1109/TBME.2014.2308552
    Ha, Sohmyung ; Kim, Chul ; Chi, Yu M. ; Akinin, Abraham ; Maier, Christoph ; Ueno, Akinori ; Cauwenberghs, Gert. / Integrated circuits and electrode interfaces for noninvasive physiological monitoring. In: IEEE Transactions on Biomedical Engineering. 2014 ; Vol. 61, No. 5. pp. 1522-1537.
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