INTEGRATE-AND-FIRE MODELS OF NERVE MEMBRANE RESPONSE TO OSCILLATORY INPUT.

J. P. Keener, F. C. Hoppensteadt, J. Rinzel

Research output: Contribution to journalArticle

Abstract

Nerve membranes exhibit curious responses to alternating current stimulation, among which are phase locking, as well as reponses without apparent periodic pattern. These phenomena are investigated by presenting a complete analysis of the response to periodic input of an integrate-and-fire model, which is a simplified version of the Hodgkin-Huxley theory for space clamped nerves.

Original languageEnglish (US)
Pages (from-to)503-517
Number of pages15
JournalSIAM Journal on Applied Mathematics
Volume41
Issue number3
DOIs
StatePublished - Jan 1 1981

ASJC Scopus subject areas

  • Applied Mathematics

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