Insomnia symptoms and HIV infection among participants in the women's interagency HIV study

Girardin Jean-Louis, Kathleen M. Weber, Bradley E. Aouizerat, Alexandra M. Levine, Pauline M. Maki, Chenglong Liu, Kathryn M. Anastos, Joel Milam, Keri N. Althoff, Tracey E. Wilson

Research output: Contribution to journalArticle

Abstract

Objectives: This study assessed the prevalence of insomnia symptoms among women with and without HIV-infection and examined factors associated with insomnia. Design: Participants (n = 1682) were enrolled in the Women's Interagency HIV Study (WIHS); 69% were infected with HIV. This was a crosssectional analysis of data from standardized interviewer-administered instruments and physical/gynecological exams. Analysis focused on sociodemographics, sleep measures, depressive symptoms, drug use, alcohol consumption, medications, and HIV-related clinical variables. Women were classified as having symptoms of insomnia if they reported either difficulty initiating sleep, difficulty maintaining sleep, or early morning awakening ≥ 3 times a week in the past 2 weeks. Results: Overall, HIV-infected women were 17% more likely to endorse insomnia symptoms than uninfected women (OR = 1.17, 95% CI: 1.04-1.34, P <0.05). The adjusted prevalence of insomnia symptoms varied by HIV status and age groups. Among women ages 31-40 years, those with HIV infection were 26% more likely to endorse insomnia symptoms than their counterparts (OR = 1.26, 95% CI: 1.01-1.59, P <0.05). No significant differences were observed in the likelihood of reporting insomnia symptoms based on HIV treatment type. Multivariate-adjusted regression analyses showed that depression was the most consistent and significant independent predictor of the likelihood of reporting insomnia symptoms across all age strata. Conclusions: Insomnia symptoms are common among both HIV-infected and uninfected women. Prevalence of insomnia did not vary significantly by HIV status, except among younger women. Younger women with HIV infection are at greater risk for experiencing insomnia symptoms.

Original languageEnglish (US)
Pages (from-to)131-137
Number of pages7
JournalSleep
Volume35
Issue number1
DOIs
StatePublished - 2012

Fingerprint

Sleep Initiation and Maintenance Disorders
HIV Infections
HIV
Sleep
Depression
Gynecological Examination
Alcohol Drinking
Age Groups
Cross-Sectional Studies
Regression Analysis
Interviews

Keywords

  • HIV infection
  • Insomnia
  • Sleep
  • Women

ASJC Scopus subject areas

  • Physiology (medical)
  • Clinical Neurology

Cite this

Jean-Louis, G., Weber, K. M., Aouizerat, B. E., Levine, A. M., Maki, P. M., Liu, C., ... Wilson, T. E. (2012). Insomnia symptoms and HIV infection among participants in the women's interagency HIV study. Sleep, 35(1), 131-137. https://doi.org/10.5665/sleep.1602

Insomnia symptoms and HIV infection among participants in the women's interagency HIV study. / Jean-Louis, Girardin; Weber, Kathleen M.; Aouizerat, Bradley E.; Levine, Alexandra M.; Maki, Pauline M.; Liu, Chenglong; Anastos, Kathryn M.; Milam, Joel; Althoff, Keri N.; Wilson, Tracey E.

In: Sleep, Vol. 35, No. 1, 2012, p. 131-137.

Research output: Contribution to journalArticle

Jean-Louis, G, Weber, KM, Aouizerat, BE, Levine, AM, Maki, PM, Liu, C, Anastos, KM, Milam, J, Althoff, KN & Wilson, TE 2012, 'Insomnia symptoms and HIV infection among participants in the women's interagency HIV study', Sleep, vol. 35, no. 1, pp. 131-137. https://doi.org/10.5665/sleep.1602
Jean-Louis, Girardin ; Weber, Kathleen M. ; Aouizerat, Bradley E. ; Levine, Alexandra M. ; Maki, Pauline M. ; Liu, Chenglong ; Anastos, Kathryn M. ; Milam, Joel ; Althoff, Keri N. ; Wilson, Tracey E. / Insomnia symptoms and HIV infection among participants in the women's interagency HIV study. In: Sleep. 2012 ; Vol. 35, No. 1. pp. 131-137.
@article{4bd06dafcac74e4cb104d36a4ebf9ca4,
title = "Insomnia symptoms and HIV infection among participants in the women's interagency HIV study",
abstract = "Objectives: This study assessed the prevalence of insomnia symptoms among women with and without HIV-infection and examined factors associated with insomnia. Design: Participants (n = 1682) were enrolled in the Women's Interagency HIV Study (WIHS); 69{\%} were infected with HIV. This was a crosssectional analysis of data from standardized interviewer-administered instruments and physical/gynecological exams. Analysis focused on sociodemographics, sleep measures, depressive symptoms, drug use, alcohol consumption, medications, and HIV-related clinical variables. Women were classified as having symptoms of insomnia if they reported either difficulty initiating sleep, difficulty maintaining sleep, or early morning awakening ≥ 3 times a week in the past 2 weeks. Results: Overall, HIV-infected women were 17{\%} more likely to endorse insomnia symptoms than uninfected women (OR = 1.17, 95{\%} CI: 1.04-1.34, P <0.05). The adjusted prevalence of insomnia symptoms varied by HIV status and age groups. Among women ages 31-40 years, those with HIV infection were 26{\%} more likely to endorse insomnia symptoms than their counterparts (OR = 1.26, 95{\%} CI: 1.01-1.59, P <0.05). No significant differences were observed in the likelihood of reporting insomnia symptoms based on HIV treatment type. Multivariate-adjusted regression analyses showed that depression was the most consistent and significant independent predictor of the likelihood of reporting insomnia symptoms across all age strata. Conclusions: Insomnia symptoms are common among both HIV-infected and uninfected women. Prevalence of insomnia did not vary significantly by HIV status, except among younger women. Younger women with HIV infection are at greater risk for experiencing insomnia symptoms.",
keywords = "HIV infection, Insomnia, Sleep, Women",
author = "Girardin Jean-Louis and Weber, {Kathleen M.} and Aouizerat, {Bradley E.} and Levine, {Alexandra M.} and Maki, {Pauline M.} and Chenglong Liu and Anastos, {Kathryn M.} and Joel Milam and Althoff, {Keri N.} and Wilson, {Tracey E.}",
year = "2012",
doi = "10.5665/sleep.1602",
language = "English (US)",
volume = "35",
pages = "131--137",
journal = "Sleep",
issn = "0161-8105",
publisher = "American Academy of Sleep Medicine",
number = "1",

}

TY - JOUR

T1 - Insomnia symptoms and HIV infection among participants in the women's interagency HIV study

AU - Jean-Louis, Girardin

AU - Weber, Kathleen M.

AU - Aouizerat, Bradley E.

AU - Levine, Alexandra M.

AU - Maki, Pauline M.

AU - Liu, Chenglong

AU - Anastos, Kathryn M.

AU - Milam, Joel

AU - Althoff, Keri N.

AU - Wilson, Tracey E.

PY - 2012

Y1 - 2012

N2 - Objectives: This study assessed the prevalence of insomnia symptoms among women with and without HIV-infection and examined factors associated with insomnia. Design: Participants (n = 1682) were enrolled in the Women's Interagency HIV Study (WIHS); 69% were infected with HIV. This was a crosssectional analysis of data from standardized interviewer-administered instruments and physical/gynecological exams. Analysis focused on sociodemographics, sleep measures, depressive symptoms, drug use, alcohol consumption, medications, and HIV-related clinical variables. Women were classified as having symptoms of insomnia if they reported either difficulty initiating sleep, difficulty maintaining sleep, or early morning awakening ≥ 3 times a week in the past 2 weeks. Results: Overall, HIV-infected women were 17% more likely to endorse insomnia symptoms than uninfected women (OR = 1.17, 95% CI: 1.04-1.34, P <0.05). The adjusted prevalence of insomnia symptoms varied by HIV status and age groups. Among women ages 31-40 years, those with HIV infection were 26% more likely to endorse insomnia symptoms than their counterparts (OR = 1.26, 95% CI: 1.01-1.59, P <0.05). No significant differences were observed in the likelihood of reporting insomnia symptoms based on HIV treatment type. Multivariate-adjusted regression analyses showed that depression was the most consistent and significant independent predictor of the likelihood of reporting insomnia symptoms across all age strata. Conclusions: Insomnia symptoms are common among both HIV-infected and uninfected women. Prevalence of insomnia did not vary significantly by HIV status, except among younger women. Younger women with HIV infection are at greater risk for experiencing insomnia symptoms.

AB - Objectives: This study assessed the prevalence of insomnia symptoms among women with and without HIV-infection and examined factors associated with insomnia. Design: Participants (n = 1682) were enrolled in the Women's Interagency HIV Study (WIHS); 69% were infected with HIV. This was a crosssectional analysis of data from standardized interviewer-administered instruments and physical/gynecological exams. Analysis focused on sociodemographics, sleep measures, depressive symptoms, drug use, alcohol consumption, medications, and HIV-related clinical variables. Women were classified as having symptoms of insomnia if they reported either difficulty initiating sleep, difficulty maintaining sleep, or early morning awakening ≥ 3 times a week in the past 2 weeks. Results: Overall, HIV-infected women were 17% more likely to endorse insomnia symptoms than uninfected women (OR = 1.17, 95% CI: 1.04-1.34, P <0.05). The adjusted prevalence of insomnia symptoms varied by HIV status and age groups. Among women ages 31-40 years, those with HIV infection were 26% more likely to endorse insomnia symptoms than their counterparts (OR = 1.26, 95% CI: 1.01-1.59, P <0.05). No significant differences were observed in the likelihood of reporting insomnia symptoms based on HIV treatment type. Multivariate-adjusted regression analyses showed that depression was the most consistent and significant independent predictor of the likelihood of reporting insomnia symptoms across all age strata. Conclusions: Insomnia symptoms are common among both HIV-infected and uninfected women. Prevalence of insomnia did not vary significantly by HIV status, except among younger women. Younger women with HIV infection are at greater risk for experiencing insomnia symptoms.

KW - HIV infection

KW - Insomnia

KW - Sleep

KW - Women

UR - http://www.scopus.com/inward/record.url?scp=84863041262&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84863041262&partnerID=8YFLogxK

U2 - 10.5665/sleep.1602

DO - 10.5665/sleep.1602

M3 - Article

VL - 35

SP - 131

EP - 137

JO - Sleep

JF - Sleep

SN - 0161-8105

IS - 1

ER -