Insertion of CO2 Mediated by a (Xantphos)NiI–Alkyl Species

Justin B. Diccianni, Chunhua T. Hu, Tianning Diao

Research output: Contribution to journalArticle

Abstract

The incorporation of CO2 into organometallic and organic molecules represents a sustainable way to prepare carboxylates. The mechanism of reductive carboxylation of alkyl halides has been proposed to proceed through the reduction of NiII to NiI by either Zn or Mn, followed by CO2 insertion into NiI-alkyl species. No experimental evidence has been previously established to support the two proposed steps. Demonstrated herein is that the direct reduction of (tBu-Xantphos)NiIIBr2 by Zn affords NiI species. (tBu-Xantphos)NiI-Me and (tBu-Xantphos)NiI-Et complexes undergo fast insertion of CO2 at 22 °C. The substantially faster rate, relative to that of NiII complexes, serves as the long-sought-after experimental support for the proposed mechanisms of Ni-catalyzed carboxylation reactions.

Original languageEnglish (US)
JournalAngewandte Chemie - International Edition
DOIs
StateAccepted/In press - Jan 1 2019

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Carboxylation
Organometallics
Molecules
xantphos

Keywords

  • carbon dioxide
  • nickel
  • reaction mechanisms
  • reduction
  • structure elucidation

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

Cite this

Insertion of CO2 Mediated by a (Xantphos)NiI–Alkyl Species. / Diccianni, Justin B.; Hu, Chunhua T.; Diao, Tianning.

In: Angewandte Chemie - International Edition, 01.01.2019.

Research output: Contribution to journalArticle

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