Inflammatory bowel disease in patients with celiac disease

Alice Yang, Yu Chen, Ellen Scherl, Alfred I. Neugut, Govind Bhagat, Peter H R Green

Research output: Contribution to journalReview article

Abstract

Background: Several case reports and series report an association between celiac disease and inflammatory bowel disease (IBD); however, there is no current data assessing this association. We therefore studied the occurrence of these conditions in a cohort of patients with celiac disease seen at a referral center. Methods: A database of patients with celiac disease seen between 1981 and 2002 was analyzed. Only biopsy-proven adults were included. Patients who had endoscopic and pathologic evidence of IBD were identified, and their pathology was reviewed. Age- and sex-adjusted prevalence rate ratios were determined by comparing results with population-based prevalence data. Results: Among 455 patients with celiac disease, IBD was identified in 10 (5 had ulcerative colitis and 5 had Crohn's disease). This represented an age- and sex-adjusted prevalence rate ratio for ulcerative colitis of 3.56 (95% confidence interval, 1.48-8.56) and for Crohn's disease of 8.49 (95% confidence interval, 3.53-20.42). Conclusion: Within our cohort of patients with celiac disease, IBD was significantly more common than in the general population.

Original languageEnglish (US)
Pages (from-to)528-532
Number of pages5
JournalInflammatory Bowel Diseases
Volume11
Issue number6
DOIs
StatePublished - Jun 2005

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Celiac Disease
Inflammatory Bowel Diseases
Ulcerative Colitis
Crohn Disease
Confidence Intervals
Population
Referral and Consultation
Databases
Pathology
Biopsy

Keywords

  • Celiac disease
  • Inflammatory bowel disease

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Inflammatory bowel disease in patients with celiac disease. / Yang, Alice; Chen, Yu; Scherl, Ellen; Neugut, Alfred I.; Bhagat, Govind; Green, Peter H R.

In: Inflammatory Bowel Diseases, Vol. 11, No. 6, 06.2005, p. 528-532.

Research output: Contribution to journalReview article

Yang, A, Chen, Y, Scherl, E, Neugut, AI, Bhagat, G & Green, PHR 2005, 'Inflammatory bowel disease in patients with celiac disease', Inflammatory Bowel Diseases, vol. 11, no. 6, pp. 528-532. https://doi.org/10.1097/01.MIB.0000161308.65951.db
Yang, Alice ; Chen, Yu ; Scherl, Ellen ; Neugut, Alfred I. ; Bhagat, Govind ; Green, Peter H R. / Inflammatory bowel disease in patients with celiac disease. In: Inflammatory Bowel Diseases. 2005 ; Vol. 11, No. 6. pp. 528-532.
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