Incorporation of unnatural amino acids for synthetic biology

Natalya Voloshchuk, Jin Montclare

Research output: Contribution to journalArticle

Abstract

The challenge of synthetic biology lies in the construction of artificial cellular systems. This requires the development of modular "parts" that can be integrated into living systems to elicit an artificial, yet programmed, response or function. The development of methods to engineer proteins bearing unnatural amino acids (UAAs) provides essential components that may address this challenge. Here we review the emerging strategies for incorporating UAAs into proteins with the endgame of engineering artificial cells and organisms.

Original languageEnglish (US)
Pages (from-to)65-80
Number of pages16
JournalMolecular BioSystems
Volume6
Issue number1
DOIs
StatePublished - 2009

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Synthetic Biology
Artificial Cells
Amino Acids
Essential Amino Acids
Proteins

ASJC Scopus subject areas

  • Biotechnology
  • Molecular Biology

Cite this

Incorporation of unnatural amino acids for synthetic biology. / Voloshchuk, Natalya; Montclare, Jin.

In: Molecular BioSystems, Vol. 6, No. 1, 2009, p. 65-80.

Research output: Contribution to journalArticle

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