In vivo Effects of a SnF2 Gel on Acid-softened Enamel

J. W. Clark, A. Quiros, R. E. Corpron, Frederick More, C. J. Kowalski

Research output: Contribution to journalArticle

Abstract

The purpose of this investigation was to study the intra-oral rehardening of acid-softened enamel and fluoride uptake from SnF2 gel. Bovine enamel slabs were softened with 0.1 mol/L lactate buffer at pH 4.0 for 14 hrs and then mounted in a mandibular removable Hawley appliance. Control slabs were worn for 96 hrs by seven adult males whose teeth were brushed daily with a fluoride-free dentifrice. Test slabs were exposed once/day to 0.4% SnF2 gel. The gel was swabbed onto the slabs for one minute before being replaced in the mouth unrinsed. The natural dentition was brushed 4x/day with a fluoride-free dentifrice. Microhardness testing was performed after a intra-oral exposure (IOE) and after acid-resistance-testing (ART) following immersion in 0.01 mol/L lactate buffer for 24 hrs at pH of 4.0. Fluoride uptake was measured on separate controls, test slabs, and test slabs after ART, with 0.5 mol/L HClO4 etches of from 15 to 60 sec. The F content was measured with a F-ion-specific electrode and the phosphate content by spectrophotometry. Following IOE, microhardness recovery was 35.6% for control and 37.9% for test slabs, and control slabs retained 1.4% resistance to acid, as compared with 18.6% for the test slabs. The F content of control slabs was significantly less than that of SnF2-treated slabs from 5 to 60 μm in depth, and the F content of SnF2-treated slabs after ART was significantly less at depths of from 5 to 35 μm than that of SnF2-treated slabs not exposed to ART. Both control and SnF 2 enamel slabs demonstrated rehardening after IOE, but only SnF 2-treated enamel retained a significant fraction of that rehardening after ART.

Original languageEnglish (US)
Pages (from-to)698-702
Number of pages5
JournalJournal of Dental Research
Volume65
Issue number5
DOIs
StatePublished - 1986

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Dental Enamel
Gels
Acids
Fluorides
Dentifrices
Lactic Acid
Buffers
Dentition
Spectrophotometry
Immersion
Mouth
Tooth
Electrodes
Phosphates
Ions

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

In vivo Effects of a SnF2 Gel on Acid-softened Enamel. / Clark, J. W.; Quiros, A.; Corpron, R. E.; More, Frederick; Kowalski, C. J.

In: Journal of Dental Research, Vol. 65, No. 5, 1986, p. 698-702.

Research output: Contribution to journalArticle

Clark, JW, Quiros, A, Corpron, RE, More, F & Kowalski, CJ 1986, 'In vivo Effects of a SnF2 Gel on Acid-softened Enamel', Journal of Dental Research, vol. 65, no. 5, pp. 698-702. https://doi.org/10.1177/00220345860650051401
Clark, J. W. ; Quiros, A. ; Corpron, R. E. ; More, Frederick ; Kowalski, C. J. / In vivo Effects of a SnF2 Gel on Acid-softened Enamel. In: Journal of Dental Research. 1986 ; Vol. 65, No. 5. pp. 698-702.
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