Idiomatic (gene) expressions

Research output: Contribution to journalArticle

Abstract

Hidden among the myriad nucleotide variants that constitute each species' gene pool are a few variants that contribute to phenotypic variation. Many of these differences that make a difference are non-coding cisregulatory variants, which, unlike coding variants, can only be identified through laborious experimental analysis. Recently, Cowles et al. described a screening method that does an end-run around this problem by searching for genes whose cis regulation varies without having to find the polymorphic nucleotides that influence transcription. While we will continue to require a diverse arsenal of experimental methods, this versatile method will speed the identification of functional genetic variation.

Original languageEnglish (US)
Pages (from-to)421-424
Number of pages4
JournalBioEssays
Volume25
Issue number5
DOIs
StatePublished - May 1 2003

Fingerprint

Gene expression
Nucleotides
Genes
Arsenals
Gene Expression
gene expression
Transcription
nucleotides
Gene Pool
Screening
phenotypic variation
transcription (genetics)
methodology
screening
genetic variation
genes

ASJC Scopus subject areas

  • Agricultural and Biological Sciences (miscellaneous)
  • Plant Science
  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry
  • Cell Biology
  • Developmental Biology
  • Neuroscience (miscellaneous)

Cite this

Idiomatic (gene) expressions. / Rockman, Matthew V.

In: BioEssays, Vol. 25, No. 5, 01.05.2003, p. 421-424.

Research output: Contribution to journalArticle

Rockman, Matthew V. / Idiomatic (gene) expressions. In: BioEssays. 2003 ; Vol. 25, No. 5. pp. 421-424.
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