Identification and characterization of Nasonia Pax genes

R. G. Keller, C. Desplan, M. I. Rosenberg

Research output: Contribution to journalArticle

Abstract

Pax genes are a group of critical developmental transcriptional regulators in both invertebrates and vertebrates, characterized by the presence of a paired DNA-binding domain. Pax proteins also often contain an octapeptide motif and a C-terminal homeodomain. The genome of Nasonia vitripennis (Hymenoptera) has recently become available, and analysis of this genome alongside Apis mellifera allowed us to contribute to the phylogeny of this gene family in insects. Nasonia, a parasitic wasp, has independently evolved a similar mode of development to that of the well-studied Drosophila, making it an excellent model system for comparative studies of developmental gene networks. We report the characterization of the seven Nasonia Pax genes. We describe their genomic organization, and the embryonic expression of three of them, and uncover wider conservation of the octapeptide motif than previously described.

Original languageEnglish (US)
Pages (from-to)109-120
Number of pages12
JournalInsect Molecular Biology
Volume19
Issue numberSUPPL. 1
DOIs
StatePublished - Feb 2010

Fingerprint

Nasonia
Genome
Nasonia vitripennis
Genes
Developmental Genes
Wasps
Hymenoptera
DNA-binding domains
genome
genes
Gene Regulatory Networks
Bees
Invertebrates
Phylogeny
Apis mellifera
Drosophila
Insects
Vertebrates
transcription factors
invertebrates

Keywords

  • Development
  • Evolution
  • Nasonia
  • Octapeptide
  • Pax

ASJC Scopus subject areas

  • Insect Science
  • Molecular Biology
  • Genetics

Cite this

Identification and characterization of Nasonia Pax genes. / Keller, R. G.; Desplan, C.; Rosenberg, M. I.

In: Insect Molecular Biology, Vol. 19, No. SUPPL. 1, 02.2010, p. 109-120.

Research output: Contribution to journalArticle

Keller, R. G. ; Desplan, C. ; Rosenberg, M. I. / Identification and characterization of Nasonia Pax genes. In: Insect Molecular Biology. 2010 ; Vol. 19, No. SUPPL. 1. pp. 109-120.
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