Histomorphometry and bone mechanical property evolution around different implant systems at early healing stages: An experimental study in dogs

Ryo Jimbo, Rodolfo Anchieta, Marta Baldassarri, Rodrigo Granato, Charles Marin, Hellen S. Teixeira, Nick Tovar, Stefan Vandeweghe, Malvin N. Janal, Paulo G. Coelho

Research output: Contribution to journalArticle

Abstract

PURPOSE:: Commercial implants differ at macro-, micro-, and nanolevels, which makes it difficult to distinguish their effect on osseointegration. The aim of this study was to evaluate the early integration of 5 commercially available implants (Astra OsseoSpeed, Straumann SLA, Intra-Lock Blossom Ossean, Nobel Active, and OsseoFix) by histomorphometry and nanoindentation. MATERIALS AND METHODS:: Implants were installed in the tibiae of 18 beagle dogs. Samples were retrieved at 1, 3, and 6 weeks (n = 6 for each time point) and were histologically and nanomechanically evaluated. RESULTS:: The results presented that both time (P < 0.01) and implant system and time interaction (P < 0.02) significantly affected the bone-to-implant contact (BIC). At 1 week, the different groups presented statistically different outcomes. No significant changes in BIC were noted thereafter. There were no significant differences in rank elastic modulus (E) or in rank hardness (H) for time (E: P > 0.80; H: P > 0.75) or implant system (E: P > 0.90; H: P > 0.85). CONCLUSIONS:: The effect of different implant designs on osseointegration was evident especially at early stages of bone healing.

Original languageEnglish (US)
Pages (from-to)596-603
Number of pages8
JournalImplant dentistry
Volume22
Issue number6
DOIs
StatePublished - Dec 1 2013

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Keywords

  • histology
  • nanoindentation
  • osseointegration

ASJC Scopus subject areas

  • Oral Surgery

Cite this

Jimbo, R., Anchieta, R., Baldassarri, M., Granato, R., Marin, C., Teixeira, H. S., Tovar, N., Vandeweghe, S., Janal, M. N., & Coelho, P. G. (2013). Histomorphometry and bone mechanical property evolution around different implant systems at early healing stages: An experimental study in dogs. Implant dentistry, 22(6), 596-603. https://doi.org/10.1097/ID.0b013e31829f1f4b