Histological findings of revascularized/revitalized immature permanent molar with apical periodontitis using platelet-rich plasma

Gabriela Martin, Domenico Ricucci, Jennifer Gibbs, Louis Lin

Research output: Contribution to journalArticle

Abstract

Introduction: An immature mandibular right first molar (#30) with apical periodontitis of a 9-year-old boy was treated with a revascularization/ revitalization procedure using either a mixture of platelet-rich plasma (PRP) and a blood clot or a blood clot alone on the same tooth. Methods: Tooth #30 fractured 2 years and 1 month after the revascularization/revitalization procedure and could not be saved. The tooth was extracted and processed for histologic examination to determine the nature of the tissues that formed in the canals. Results: Clinically, the endodontic treatment of the case was successful based on the resolution of apical periodontitis and the absence of clinical signs and symptoms. Histologically, the tissues formed in the distal and mesial canals were mineralized tissue similar to cementoid/osteoid tissue and uninflamed fibrous connective tissue regardless of PRP or no PRP treatment. No pulp-like tissue characterized by the presence of odontoblast-like cells polarized along the dentin-like mineralized tissue was observed. Conclusions: The tissues formed in the canals were mineralized tissue and some fibrous connective tissue. No pulp-like tissue characterized by the presence of odontoblast-like cells was observed lining the dentin-like mineralized tissue.

Original languageEnglish (US)
Pages (from-to)138-144
Number of pages7
JournalJournal of Endodontics
Volume39
Issue number1
DOIs
StatePublished - Jan 2013

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Periapical Periodontitis
Platelet-Rich Plasma
Odontoblasts
Tooth
Dentin
Connective Tissue
Thrombosis
Endodontics
Signs and Symptoms

Keywords

  • Apical periodontitis
  • cementoid/osteoid tissue
  • immature permanent tooth
  • platelet-rich plasma
  • revascularization/revitalization

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Histological findings of revascularized/revitalized immature permanent molar with apical periodontitis using platelet-rich plasma. / Martin, Gabriela; Ricucci, Domenico; Gibbs, Jennifer; Lin, Louis.

In: Journal of Endodontics, Vol. 39, No. 1, 01.2013, p. 138-144.

Research output: Contribution to journalArticle

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