Hepatitis C virus infection: Prevalence, risk factors, and prevention opportunities among young injection drug users in Chicago, 1997-1999

Lorna Thorpe, Lawrence J. Ouellet, Jennie R. Levy, Ian T. Williams, Edgar R. Monterroso

Research output: Contribution to journalArticle

Abstract

The prevalence, risk factors, and prevention opportunities of hepatitis C virus (HCV) infection were studied in a large sample of 698 young adult injection drug users (IDUs) in Chicago, 18-30 years old. Participants were recruited between 1997 and 1999 by using street outreach, targeted advertising, and chain-referral methods. HCV infection prevalence was 27% and was strongly associated with both age and duration of injecting (P< .001). In multivariable analysis, sexual behaviors were unrelated to seropositivity. Independent drug-related risk factors included frequent injection, heavy crack smoking, injecting in a shooting gallery, and syringe-mediated sharing. Urban residents were more likely than suburban residents to be infected. Most research on hepatitis C has shown rapid spread of infection among IDUs, but these findings underscore that opportunities to identify IDUs uninfected with HCV may be greater than assumed and emphasize the need to target younger, newer IDUs.

Original languageEnglish (US)
Pages (from-to)1588-1594
Number of pages7
JournalJournal of Infectious Diseases
Volume182
Issue number6
DOIs
StatePublished - 2000

Fingerprint

Virus Diseases
Drug Users
Hepacivirus
Injections
Needle Sharing
Hepatitis C
Sexual Behavior
Young Adult
Referral and Consultation
Smoking
Infection
Research
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases

Cite this

Hepatitis C virus infection : Prevalence, risk factors, and prevention opportunities among young injection drug users in Chicago, 1997-1999. / Thorpe, Lorna; Ouellet, Lawrence J.; Levy, Jennie R.; Williams, Ian T.; Monterroso, Edgar R.

In: Journal of Infectious Diseases, Vol. 182, No. 6, 2000, p. 1588-1594.

Research output: Contribution to journalArticle

Thorpe, Lorna ; Ouellet, Lawrence J. ; Levy, Jennie R. ; Williams, Ian T. ; Monterroso, Edgar R. / Hepatitis C virus infection : Prevalence, risk factors, and prevention opportunities among young injection drug users in Chicago, 1997-1999. In: Journal of Infectious Diseases. 2000 ; Vol. 182, No. 6. pp. 1588-1594.
@article{1247959de17a402a9df918c36ce47f01,
title = "Hepatitis C virus infection: Prevalence, risk factors, and prevention opportunities among young injection drug users in Chicago, 1997-1999",
abstract = "The prevalence, risk factors, and prevention opportunities of hepatitis C virus (HCV) infection were studied in a large sample of 698 young adult injection drug users (IDUs) in Chicago, 18-30 years old. Participants were recruited between 1997 and 1999 by using street outreach, targeted advertising, and chain-referral methods. HCV infection prevalence was 27{\%} and was strongly associated with both age and duration of injecting (P< .001). In multivariable analysis, sexual behaviors were unrelated to seropositivity. Independent drug-related risk factors included frequent injection, heavy crack smoking, injecting in a shooting gallery, and syringe-mediated sharing. Urban residents were more likely than suburban residents to be infected. Most research on hepatitis C has shown rapid spread of infection among IDUs, but these findings underscore that opportunities to identify IDUs uninfected with HCV may be greater than assumed and emphasize the need to target younger, newer IDUs.",
author = "Lorna Thorpe and Ouellet, {Lawrence J.} and Levy, {Jennie R.} and Williams, {Ian T.} and Monterroso, {Edgar R.}",
year = "2000",
doi = "10.1086/317607",
language = "English (US)",
volume = "182",
pages = "1588--1594",
journal = "Journal of Infectious Diseases",
issn = "0022-1899",
publisher = "Oxford University Press",
number = "6",

}

TY - JOUR

T1 - Hepatitis C virus infection

T2 - Prevalence, risk factors, and prevention opportunities among young injection drug users in Chicago, 1997-1999

AU - Thorpe, Lorna

AU - Ouellet, Lawrence J.

AU - Levy, Jennie R.

AU - Williams, Ian T.

AU - Monterroso, Edgar R.

PY - 2000

Y1 - 2000

N2 - The prevalence, risk factors, and prevention opportunities of hepatitis C virus (HCV) infection were studied in a large sample of 698 young adult injection drug users (IDUs) in Chicago, 18-30 years old. Participants were recruited between 1997 and 1999 by using street outreach, targeted advertising, and chain-referral methods. HCV infection prevalence was 27% and was strongly associated with both age and duration of injecting (P< .001). In multivariable analysis, sexual behaviors were unrelated to seropositivity. Independent drug-related risk factors included frequent injection, heavy crack smoking, injecting in a shooting gallery, and syringe-mediated sharing. Urban residents were more likely than suburban residents to be infected. Most research on hepatitis C has shown rapid spread of infection among IDUs, but these findings underscore that opportunities to identify IDUs uninfected with HCV may be greater than assumed and emphasize the need to target younger, newer IDUs.

AB - The prevalence, risk factors, and prevention opportunities of hepatitis C virus (HCV) infection were studied in a large sample of 698 young adult injection drug users (IDUs) in Chicago, 18-30 years old. Participants were recruited between 1997 and 1999 by using street outreach, targeted advertising, and chain-referral methods. HCV infection prevalence was 27% and was strongly associated with both age and duration of injecting (P< .001). In multivariable analysis, sexual behaviors were unrelated to seropositivity. Independent drug-related risk factors included frequent injection, heavy crack smoking, injecting in a shooting gallery, and syringe-mediated sharing. Urban residents were more likely than suburban residents to be infected. Most research on hepatitis C has shown rapid spread of infection among IDUs, but these findings underscore that opportunities to identify IDUs uninfected with HCV may be greater than assumed and emphasize the need to target younger, newer IDUs.

UR - http://www.scopus.com/inward/record.url?scp=0033724990&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033724990&partnerID=8YFLogxK

U2 - 10.1086/317607

DO - 10.1086/317607

M3 - Article

C2 - 11069228

AN - SCOPUS:0033724990

VL - 182

SP - 1588

EP - 1594

JO - Journal of Infectious Diseases

JF - Journal of Infectious Diseases

SN - 0022-1899

IS - 6

ER -