Hebbian reverberations in emotional memory micro circuits

Luke R. Johnson, Joseph Ledoux, Valérie Doyère

Research output: Contribution to journalArticle

Abstract

The study of memory in most behavioral paradigms, including emotional memory paradigms, has focused on the feed forward components that underlie Hebb's first postulate, associative synaptic plasticity. Hebb's second postulate argues that activated ensembles of neurons reverberate in order to provide temporal coordination of different neural signals, and thereby facilitate coincidence detection. Recent evidence from our groups has suggested that the lateral amygdala (LA) contains recurrent microcircuits and that these may reverberate. Additionally this reverberant activity is precisely timed with latencies that would facilitate coincidence detection between cortical and sub cortical afferents to the LA. Thus, recent data at the microcircuit level in the amygdala provide some physiological evidence in support of the second Hebbian postulate.

Original languageEnglish (US)
Pages (from-to)198-205
Number of pages8
JournalFrontiers in Neuroscience
Volume3
Issue numberSEP
DOIs
StatePublished - 2009

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Amygdala
Neuronal Plasticity
Neurons

Keywords

  • Amygdala
  • Ensembles
  • Fear
  • Network
  • Recurrent

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Hebbian reverberations in emotional memory micro circuits. / Johnson, Luke R.; Ledoux, Joseph; Doyère, Valérie.

In: Frontiers in Neuroscience, Vol. 3, No. SEP, 2009, p. 198-205.

Research output: Contribution to journalArticle

Johnson, Luke R. ; Ledoux, Joseph ; Doyère, Valérie. / Hebbian reverberations in emotional memory micro circuits. In: Frontiers in Neuroscience. 2009 ; Vol. 3, No. SEP. pp. 198-205.
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