Glycophorins, Blood Groups, and Protection from Severe Malaria

Samuel C. Wassmer, Jane M. Carlton

Research output: Contribution to journalArticle

Abstract

In Malaŵi, Malungo alibe odi is a saying that translates as: 'Malaria does not ask permission before coming in'. The recent finding of a new severe malaria resistance locus next to a cluster of glycophorin genes involved in Plasmodium falciparum erythrocyte invasion seems to suggest otherwise: that evolutionary pressure is enabling erythrocytes to lock the door to keep malaria out.

Original languageEnglish (US)
Pages (from-to)5-7
Number of pages3
JournalTrends in Parasitology
Volume32
Issue number1
DOIs
StatePublished - Jan 1 2016

Fingerprint

Glycophorin
Blood Group Antigens
Malaria
Erythrocytes
Plasmodium falciparum
Multigene Family
Pressure

Keywords

  • Genome-wide association study
  • Plasmodium falciparum malaria

ASJC Scopus subject areas

  • Infectious Diseases
  • Parasitology

Cite this

Glycophorins, Blood Groups, and Protection from Severe Malaria. / Wassmer, Samuel C.; Carlton, Jane M.

In: Trends in Parasitology, Vol. 32, No. 1, 01.01.2016, p. 5-7.

Research output: Contribution to journalArticle

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