Gender differences in acute psychomotor, cognitive, and pharmacokinetic response to alcohol

Raymond Niaura, Peter E. Nathan, William Frankenstein, Allan P. Shapiro, John Brick

Research output: Contribution to journalArticle

Abstract

This study investigated gender differences in acute response to alcohol. After practicing several cognitive and psychomotor tasks while sober, male (n = 11) and female (n= 13) social drinkers were administered a 0.65 g/kg dose of ethanol. Subjects were tested on both the ascending and descending limbs of the blood alcohol curve on measures of divided attention, short-term memory, body sway, pursuit tracking ability, and subjective level of intoxication. Blood alcohol level (BAL) was sampled frequently throughout the procedure. Females achieved consistently higher BALs than did males throughout, due mainly to higher BALs among women in the middle stage of the menstrual cycle. Women not using birth control medications also attained higher BALs than did males. When gender differences in BALs were controlled statistically, only memory functioning distinguished the groups: males recovered memory functioning more quickly on the descending limb of the blood alcohol curve than did females. Stage of menstrual cycle or use of birth control medications did not influence psychomotor or cognitive performance while women were intoxicated.

Original languageEnglish (US)
Pages (from-to)345-356
Number of pages12
JournalAddictive Behaviors
Volume12
Issue number4
DOIs
StatePublished - 1987

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Dimercaprol
Pharmacokinetics
Alcohols
Blood
Menstrual Cycle
Contraception
Data storage equipment
Extremities
Aptitude
Short-Term Memory
Ethanol

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Clinical Psychology

Cite this

Gender differences in acute psychomotor, cognitive, and pharmacokinetic response to alcohol. / Niaura, Raymond; Nathan, Peter E.; Frankenstein, William; Shapiro, Allan P.; Brick, John.

In: Addictive Behaviors, Vol. 12, No. 4, 1987, p. 345-356.

Research output: Contribution to journalArticle

Niaura, Raymond ; Nathan, Peter E. ; Frankenstein, William ; Shapiro, Allan P. ; Brick, John. / Gender differences in acute psychomotor, cognitive, and pharmacokinetic response to alcohol. In: Addictive Behaviors. 1987 ; Vol. 12, No. 4. pp. 345-356.
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