Functional organization of owl monkey lateral geniculate nucleus and visual cortex

Lawrence P. O'Keefe, Jonathan B. Levitt, Daniel C. Kiper, Robert Shapley, J. Anthony Movshon

Research output: Contribution to journalArticle

Abstract

The nocturnal, New World owl monkey (Aotus trivirgatus) has a rod- dominated retina containing only a single cone type, supporting only the most rudimentary color vision. However, it does have well-developed magnocellular (M) and parvocellular (P) retinostriate pathways and striate cortical architecture [as defined by the pattern of staining for the activity- dependent marker cytochrome oxidase (CO)] similar to that seen in diurnal primates. We recorded from single neurons in anesthetized, paralyzed owl monkeys using drifting, luminance-modulated sinusoidal gratings, comparing receptive field properties of M and P neurons in the lateral geniculate nucleus and in V1 neurons assigned to CO 'blob,' 'edge,' and 'interblob' regions and across layers. Tested with achromatic stimuli, the receptive field properties of M and P neurons resembled those reported for other primates. The contrast sensitivity of P cells in the owl monkey was similar to that of P cells in the macaque, but the contrast sensitivities of M cells in the owl monkey were markedly lower than those in the macaque. We found no differences in eye dominance, orientation, or spatial frequency tuning, temporal frequency tuning, or contrast response for V1 neurons assigned to different CO compartments; we did find fewer direction-selective cells in blobs than in other compartments. We noticed laminar differences in some receptive field properties. Cells in the supragranular layers preferred higher spatial and lower temporal frequencies and had lower contrast sensitivity than did cells in the granular and infragranular layers. Our data suggest that the receptive field properties across functional compartments in V1 are quite homogeneous, inconsistent with the notion that CO blobs anatomically segregate signals from different functional 'streams'.

Original languageEnglish (US)
Pages (from-to)594-609
Number of pages16
JournalJournal of Neurophysiology
Volume80
Issue number2
StatePublished - Aug 1998

Fingerprint

Aotidae
Geniculate Bodies
Visual Cortex
Electron Transport Complex IV
Contrast Sensitivity
Neurons
Macaca
Primates
Aotus trivirgatus
Platyrrhini
ocular Dominance
Retinal Rod Photoreceptor Cells
Color Vision
Staining and Labeling

ASJC Scopus subject areas

  • Physiology
  • Neuroscience(all)

Cite this

Functional organization of owl monkey lateral geniculate nucleus and visual cortex. / O'Keefe, Lawrence P.; Levitt, Jonathan B.; Kiper, Daniel C.; Shapley, Robert; Movshon, J. Anthony.

In: Journal of Neurophysiology, Vol. 80, No. 2, 08.1998, p. 594-609.

Research output: Contribution to journalArticle

O'Keefe, Lawrence P. ; Levitt, Jonathan B. ; Kiper, Daniel C. ; Shapley, Robert ; Movshon, J. Anthony. / Functional organization of owl monkey lateral geniculate nucleus and visual cortex. In: Journal of Neurophysiology. 1998 ; Vol. 80, No. 2. pp. 594-609.
@article{3805f8ae344f43d9a7a188bd2cd3037d,
title = "Functional organization of owl monkey lateral geniculate nucleus and visual cortex",
abstract = "The nocturnal, New World owl monkey (Aotus trivirgatus) has a rod- dominated retina containing only a single cone type, supporting only the most rudimentary color vision. However, it does have well-developed magnocellular (M) and parvocellular (P) retinostriate pathways and striate cortical architecture [as defined by the pattern of staining for the activity- dependent marker cytochrome oxidase (CO)] similar to that seen in diurnal primates. We recorded from single neurons in anesthetized, paralyzed owl monkeys using drifting, luminance-modulated sinusoidal gratings, comparing receptive field properties of M and P neurons in the lateral geniculate nucleus and in V1 neurons assigned to CO 'blob,' 'edge,' and 'interblob' regions and across layers. Tested with achromatic stimuli, the receptive field properties of M and P neurons resembled those reported for other primates. The contrast sensitivity of P cells in the owl monkey was similar to that of P cells in the macaque, but the contrast sensitivities of M cells in the owl monkey were markedly lower than those in the macaque. We found no differences in eye dominance, orientation, or spatial frequency tuning, temporal frequency tuning, or contrast response for V1 neurons assigned to different CO compartments; we did find fewer direction-selective cells in blobs than in other compartments. We noticed laminar differences in some receptive field properties. Cells in the supragranular layers preferred higher spatial and lower temporal frequencies and had lower contrast sensitivity than did cells in the granular and infragranular layers. Our data suggest that the receptive field properties across functional compartments in V1 are quite homogeneous, inconsistent with the notion that CO blobs anatomically segregate signals from different functional 'streams'.",
author = "O'Keefe, {Lawrence P.} and Levitt, {Jonathan B.} and Kiper, {Daniel C.} and Robert Shapley and Movshon, {J. Anthony}",
year = "1998",
month = "8",
language = "English (US)",
volume = "80",
pages = "594--609",
journal = "Journal of Neurophysiology",
issn = "0022-3077",
publisher = "American Physiological Society",
number = "2",

}

TY - JOUR

T1 - Functional organization of owl monkey lateral geniculate nucleus and visual cortex

AU - O'Keefe, Lawrence P.

AU - Levitt, Jonathan B.

AU - Kiper, Daniel C.

AU - Shapley, Robert

AU - Movshon, J. Anthony

PY - 1998/8

Y1 - 1998/8

N2 - The nocturnal, New World owl monkey (Aotus trivirgatus) has a rod- dominated retina containing only a single cone type, supporting only the most rudimentary color vision. However, it does have well-developed magnocellular (M) and parvocellular (P) retinostriate pathways and striate cortical architecture [as defined by the pattern of staining for the activity- dependent marker cytochrome oxidase (CO)] similar to that seen in diurnal primates. We recorded from single neurons in anesthetized, paralyzed owl monkeys using drifting, luminance-modulated sinusoidal gratings, comparing receptive field properties of M and P neurons in the lateral geniculate nucleus and in V1 neurons assigned to CO 'blob,' 'edge,' and 'interblob' regions and across layers. Tested with achromatic stimuli, the receptive field properties of M and P neurons resembled those reported for other primates. The contrast sensitivity of P cells in the owl monkey was similar to that of P cells in the macaque, but the contrast sensitivities of M cells in the owl monkey were markedly lower than those in the macaque. We found no differences in eye dominance, orientation, or spatial frequency tuning, temporal frequency tuning, or contrast response for V1 neurons assigned to different CO compartments; we did find fewer direction-selective cells in blobs than in other compartments. We noticed laminar differences in some receptive field properties. Cells in the supragranular layers preferred higher spatial and lower temporal frequencies and had lower contrast sensitivity than did cells in the granular and infragranular layers. Our data suggest that the receptive field properties across functional compartments in V1 are quite homogeneous, inconsistent with the notion that CO blobs anatomically segregate signals from different functional 'streams'.

AB - The nocturnal, New World owl monkey (Aotus trivirgatus) has a rod- dominated retina containing only a single cone type, supporting only the most rudimentary color vision. However, it does have well-developed magnocellular (M) and parvocellular (P) retinostriate pathways and striate cortical architecture [as defined by the pattern of staining for the activity- dependent marker cytochrome oxidase (CO)] similar to that seen in diurnal primates. We recorded from single neurons in anesthetized, paralyzed owl monkeys using drifting, luminance-modulated sinusoidal gratings, comparing receptive field properties of M and P neurons in the lateral geniculate nucleus and in V1 neurons assigned to CO 'blob,' 'edge,' and 'interblob' regions and across layers. Tested with achromatic stimuli, the receptive field properties of M and P neurons resembled those reported for other primates. The contrast sensitivity of P cells in the owl monkey was similar to that of P cells in the macaque, but the contrast sensitivities of M cells in the owl monkey were markedly lower than those in the macaque. We found no differences in eye dominance, orientation, or spatial frequency tuning, temporal frequency tuning, or contrast response for V1 neurons assigned to different CO compartments; we did find fewer direction-selective cells in blobs than in other compartments. We noticed laminar differences in some receptive field properties. Cells in the supragranular layers preferred higher spatial and lower temporal frequencies and had lower contrast sensitivity than did cells in the granular and infragranular layers. Our data suggest that the receptive field properties across functional compartments in V1 are quite homogeneous, inconsistent with the notion that CO blobs anatomically segregate signals from different functional 'streams'.

UR - http://www.scopus.com/inward/record.url?scp=0031840932&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031840932&partnerID=8YFLogxK

M3 - Article

C2 - 9705453

AN - SCOPUS:0031840932

VL - 80

SP - 594

EP - 609

JO - Journal of Neurophysiology

JF - Journal of Neurophysiology

SN - 0022-3077

IS - 2

ER -