Frontolimbic neural circuitry at 6 months predicts individual differences in joint attention at 9 months

Jed T. Elison, Jason J. Wolff, Debra C. Heimer, Sarah J. Paterson, Hongbin Gu, Heather C. Hazlett, Martin Styner, Guido Gerig, Joseph Piven, J. Piven, H. C. Hazlett, C. Chappell, S. Dager, A. Estes, D. Shaw, K. Botteron, R. McKinstry, J. Constantino, J. Pruett, R. Schultz & 12 others S. Paterson, L. Zwaigenbaum, A. C. Evans, D. L. Collins, G. B. Pike, P. Kostopolous, S. Das, G. Gerig, M. Styner, H. Gu, P. Sullivan, F. Wright

    Research output: Contribution to journalArticle

    Abstract

    Elucidating the neural basis of joint attention in infancy promises to yield important insights into the development of language and social cognition, and directly informs developmental models of autism. We describe a new method for evaluating responding to joint attention performance in infancy that highlights the 9- to 10-month period as a time interval of maximal individual differences. We then demonstrate that fractional anisotropy in the right uncinate fasciculus, a white matter fiber bundle connecting the amygdala to the ventral-medial prefrontal cortex and anterior temporal pole, measured in 6-month-olds predicts individual differences in responding to joint attention at 9 months of age. The white matter microstructure of the right uncinate was not related to receptive language ability at 9 months. These findings suggest that the development of core nonverbal social communication skills in infancy is largely supported by preceding developments within right lateralized frontotemporal brain systems.

    Original languageEnglish (US)
    Pages (from-to)186-197
    Number of pages12
    JournalDevelopmental Science
    Volume16
    Issue number2
    DOIs
    StatePublished - Mar 2013

    Fingerprint

    Individuality
    Nonverbal Communication
    Language Development
    Aptitude
    Anisotropy
    Autistic Disorder
    Amygdala
    Prefrontal Cortex
    Cognition
    Language
    Brain
    White Matter
    Social Skills

    ASJC Scopus subject areas

    • Developmental and Educational Psychology
    • Cognitive Neuroscience

    Cite this

    Elison, J. T., Wolff, J. J., Heimer, D. C., Paterson, S. J., Gu, H., Hazlett, H. C., ... Wright, F. (2013). Frontolimbic neural circuitry at 6 months predicts individual differences in joint attention at 9 months. Developmental Science, 16(2), 186-197. https://doi.org/10.1111/desc.12015

    Frontolimbic neural circuitry at 6 months predicts individual differences in joint attention at 9 months. / Elison, Jed T.; Wolff, Jason J.; Heimer, Debra C.; Paterson, Sarah J.; Gu, Hongbin; Hazlett, Heather C.; Styner, Martin; Gerig, Guido; Piven, Joseph; Piven, J.; Hazlett, H. C.; Chappell, C.; Dager, S.; Estes, A.; Shaw, D.; Botteron, K.; McKinstry, R.; Constantino, J.; Pruett, J.; Schultz, R.; Paterson, S.; Zwaigenbaum, L.; Evans, A. C.; Collins, D. L.; Pike, G. B.; Kostopolous, P.; Das, S.; Gerig, G.; Styner, M.; Gu, H.; Sullivan, P.; Wright, F.

    In: Developmental Science, Vol. 16, No. 2, 03.2013, p. 186-197.

    Research output: Contribution to journalArticle

    Elison, JT, Wolff, JJ, Heimer, DC, Paterson, SJ, Gu, H, Hazlett, HC, Styner, M, Gerig, G, Piven, J, Piven, J, Hazlett, HC, Chappell, C, Dager, S, Estes, A, Shaw, D, Botteron, K, McKinstry, R, Constantino, J, Pruett, J, Schultz, R, Paterson, S, Zwaigenbaum, L, Evans, AC, Collins, DL, Pike, GB, Kostopolous, P, Das, S, Gerig, G, Styner, M, Gu, H, Sullivan, P & Wright, F 2013, 'Frontolimbic neural circuitry at 6 months predicts individual differences in joint attention at 9 months', Developmental Science, vol. 16, no. 2, pp. 186-197. https://doi.org/10.1111/desc.12015
    Elison, Jed T. ; Wolff, Jason J. ; Heimer, Debra C. ; Paterson, Sarah J. ; Gu, Hongbin ; Hazlett, Heather C. ; Styner, Martin ; Gerig, Guido ; Piven, Joseph ; Piven, J. ; Hazlett, H. C. ; Chappell, C. ; Dager, S. ; Estes, A. ; Shaw, D. ; Botteron, K. ; McKinstry, R. ; Constantino, J. ; Pruett, J. ; Schultz, R. ; Paterson, S. ; Zwaigenbaum, L. ; Evans, A. C. ; Collins, D. L. ; Pike, G. B. ; Kostopolous, P. ; Das, S. ; Gerig, G. ; Styner, M. ; Gu, H. ; Sullivan, P. ; Wright, F. / Frontolimbic neural circuitry at 6 months predicts individual differences in joint attention at 9 months. In: Developmental Science. 2013 ; Vol. 16, No. 2. pp. 186-197.
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