Four-dimensional respiratory motion-resolved whole heart coronary MR angiography

Davide Piccini, Li Feng, Gabriele Bonanno, Simone Coppo, Jérôme Yerly, Ruth P. Lim, Juerg Schwitter, Daniel K. Sodickson, Ricardo Otazo, Matthias Stuber

    Research output: Contribution to journalArticle

    Abstract

    Purpose: Free-breathing whole-heart coronary MR angiography (MRA) commonly uses navigators to gate respiratory motion, resulting in lengthy and unpredictable acquisition times. Conversely, self-navigation has 100% scan efficiency, but requires motion correction over a broad range of respiratory displacements, which may introduce image artifacts. We propose replacing navigators and self-navigation with a respiratory motion-resolved reconstruction approach. Methods: Using a respiratory signal extracted directly from the imaging data, individual signal-readouts are binned according to their respiratory states. The resultant series of undersampled images are reconstructed using an extradimensional golden-angle radial sparse parallel imaging (XD-GRASP) algorithm, which exploits sparsity along the respiratory dimension. Whole-heart coronary MRA was performed in 11 volunteers and four patients with the proposed methodology. Image quality was compared with that obtained with one-dimensional respiratory self-navigation. Results: Respiratory-resolved reconstruction effectively suppressed respiratory motion artifacts. The quality score for XD-GRASP reconstructions was greater than or equal to self-navigation in 80/88 coronary segments, reaching diagnostic quality in 61/88 segments versus 41/88. Coronary sharpness and length were always superior for the respiratory-resolved datasets, reaching statistical significance (P < 0.05) in most cases. Conclusion: XD-GRASP represents an attractive alternative for handling respiratory motion in free-breathing whole heart MRI and provides an effective alternative to self-navigation. Magn Reson Med 77:1473–1484, 2017.

    Original languageEnglish (US)
    Pages (from-to)1473-1484
    Number of pages12
    JournalMagnetic resonance in medicine
    Volume77
    Issue number4
    DOIs
    StatePublished - Apr 1 2017

    Keywords

    • compressed sensing
    • coronary MRA
    • free breathing
    • motion correction
    • self-navigation
    • sparse reconstruction

    ASJC Scopus subject areas

    • Radiology Nuclear Medicine and imaging

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  • Cite this

    Piccini, D., Feng, L., Bonanno, G., Coppo, S., Yerly, J., Lim, R. P., Schwitter, J., Sodickson, D. K., Otazo, R., & Stuber, M. (2017). Four-dimensional respiratory motion-resolved whole heart coronary MR angiography. Magnetic resonance in medicine, 77(4), 1473-1484. https://doi.org/10.1002/mrm.26221