Formation and utility of azasilacyclopentadienes derived from silacyclopropenes and nitriles

Laura L. Anderson, K. A. Woerpel

Research output: Contribution to journalArticle


(Chemical Equation Presented) The copper-catalyzed insertions of nitriles into the Si-C bonds of silacyclopropenes provide azasilacyclopentadienes, which can be converted to allylic amines after reduction and protodesilylation. The enamine functionality of azasilacyclopentadienes also participates in 1,4-addition reactions and undergoes a hydroboration and oxidation sequence to form an allylic 1,2-amino alcohol.

Original languageEnglish (US)
Pages (from-to)425-428
Number of pages4
JournalOrganic Letters
Issue number2
StatePublished - Jan 15 2009


ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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