Fear and the brain: Where have we been, and where are we going?

Research output: Contribution to journalArticle

Abstract

In recent years, there has been an explosion of interest in the neural basis of emotion. Much of this enthusiasm has been triggered by studies of the amygdala and its contribution to fear. This work has shown that the amygdala detects and organizes responses to natural dangers (like predators) and learns about novel threats and the stimuli that predict their occurrence. The latter process has been studied extensively using a procedure called classical fear conditioning. This article surveys the progress that has been matte in understanding the neural basis of fear and its implications for anxiety disorders, as well as the gaps in our knowledge.

Original languageEnglish (US)
Pages (from-to)1229-1238
Number of pages10
JournalBiological Psychiatry
Volume44
Issue number12
DOIs
StatePublished - Dec 15 1998

Fingerprint

Fear
Amygdala
Brain
Classical Conditioning
Explosions
Anxiety Disorders
Emotions
Surveys and Questionnaires

Keywords

  • Amygdala
  • Anxiety
  • Conditioning
  • Fear
  • Memory

ASJC Scopus subject areas

  • Biological Psychiatry

Cite this

Fear and the brain : Where have we been, and where are we going? / Ledoux, Joseph.

In: Biological Psychiatry, Vol. 44, No. 12, 15.12.1998, p. 1229-1238.

Research output: Contribution to journalArticle

@article{b59e797b0ad6465782bf736ab8f4c23c,
title = "Fear and the brain: Where have we been, and where are we going?",
abstract = "In recent years, there has been an explosion of interest in the neural basis of emotion. Much of this enthusiasm has been triggered by studies of the amygdala and its contribution to fear. This work has shown that the amygdala detects and organizes responses to natural dangers (like predators) and learns about novel threats and the stimuli that predict their occurrence. The latter process has been studied extensively using a procedure called classical fear conditioning. This article surveys the progress that has been matte in understanding the neural basis of fear and its implications for anxiety disorders, as well as the gaps in our knowledge.",
keywords = "Amygdala, Anxiety, Conditioning, Fear, Memory",
author = "Joseph Ledoux",
year = "1998",
month = "12",
day = "15",
doi = "10.1016/S0006-3223(98)00282-0",
language = "English (US)",
volume = "44",
pages = "1229--1238",
journal = "Biological Psychiatry",
issn = "0006-3223",
publisher = "Elsevier USA",
number = "12",

}

TY - JOUR

T1 - Fear and the brain

T2 - Where have we been, and where are we going?

AU - Ledoux, Joseph

PY - 1998/12/15

Y1 - 1998/12/15

N2 - In recent years, there has been an explosion of interest in the neural basis of emotion. Much of this enthusiasm has been triggered by studies of the amygdala and its contribution to fear. This work has shown that the amygdala detects and organizes responses to natural dangers (like predators) and learns about novel threats and the stimuli that predict their occurrence. The latter process has been studied extensively using a procedure called classical fear conditioning. This article surveys the progress that has been matte in understanding the neural basis of fear and its implications for anxiety disorders, as well as the gaps in our knowledge.

AB - In recent years, there has been an explosion of interest in the neural basis of emotion. Much of this enthusiasm has been triggered by studies of the amygdala and its contribution to fear. This work has shown that the amygdala detects and organizes responses to natural dangers (like predators) and learns about novel threats and the stimuli that predict their occurrence. The latter process has been studied extensively using a procedure called classical fear conditioning. This article surveys the progress that has been matte in understanding the neural basis of fear and its implications for anxiety disorders, as well as the gaps in our knowledge.

KW - Amygdala

KW - Anxiety

KW - Conditioning

KW - Fear

KW - Memory

UR - http://www.scopus.com/inward/record.url?scp=0032535354&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032535354&partnerID=8YFLogxK

U2 - 10.1016/S0006-3223(98)00282-0

DO - 10.1016/S0006-3223(98)00282-0

M3 - Article

VL - 44

SP - 1229

EP - 1238

JO - Biological Psychiatry

JF - Biological Psychiatry

SN - 0006-3223

IS - 12

ER -