Fast model-reference current injection using RT-Linux

Robert J. Butera, Christopher G. Wilson, J. Rinzel, Jeffrey C. Smith

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The dynamic clamp, an electrophysiological experimental technique utilizing the real-time computation of simulated ion channel conductances interacting with an in vitro experiment, has recently become a popular approach in both neural and cardiac electrophysiology. This paper outlines a new software implementation of this technique, which allows for computation speeds significantly faster than previous approaches using commonplace computing hardware. Our approach uses open-source freely available software tools and is easily extensible. We also discuss implementation issues affecting performance that previously have not been discussed in the literature.

Original languageEnglish (US)
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
PublisherIEEE
Pages876
Number of pages1
Volume2
ISBN (Print)0780356756
StatePublished - 1999
EventProceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS) - Atlanta, GA, USA
Duration: Oct 13 1999Oct 16 1999

Other

OtherProceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS)
CityAtlanta, GA, USA
Period10/13/9910/16/99

Fingerprint

Clamping devices
Ion Channels
Hardware
Ions
Experiments
Linux
Cardiac Electrophysiology

ASJC Scopus subject areas

  • Bioengineering

Cite this

Butera, R. J., Wilson, C. G., Rinzel, J., & Smith, J. C. (1999). Fast model-reference current injection using RT-Linux. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (Vol. 2, pp. 876). IEEE.

Fast model-reference current injection using RT-Linux. / Butera, Robert J.; Wilson, Christopher G.; Rinzel, J.; Smith, Jeffrey C.

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 2 IEEE, 1999. p. 876.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Butera, RJ, Wilson, CG, Rinzel, J & Smith, JC 1999, Fast model-reference current injection using RT-Linux. in Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. vol. 2, IEEE, pp. 876, Proceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS), Atlanta, GA, USA, 10/13/99.
Butera RJ, Wilson CG, Rinzel J, Smith JC. Fast model-reference current injection using RT-Linux. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 2. IEEE. 1999. p. 876
Butera, Robert J. ; Wilson, Christopher G. ; Rinzel, J. ; Smith, Jeffrey C. / Fast model-reference current injection using RT-Linux. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 2 IEEE, 1999. pp. 876
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