Expression profile of Ldh-a in the developing rat Rattus norvegicus testis suggests regulation at the translational level

Kourosh Salehi-Ashtiani, Erwin Goldberg

    Research output: Contribution to journalArticle

    Abstract

    Expression of Ldh-a and Ldh-c mRNAs was examined in the rat testis. The mRNA levels of both Ldh-a and Ldh-c increase during testicular maturation. In the adult testis, Ldh-a mRNA is expressed maximally in primary spermatocytes. Comparison of the Ldh-a mRNA expression profile with its translation product suggests that this gene is translationally down-regulated during spermatogenesis.

    Original languageEnglish (US)
    Pages (from-to)623-627
    Number of pages5
    JournalComparative Biochemistry and Physiology -- Part B: Biochemistry and
    Volume110
    Issue number3
    DOIs
    StatePublished - Jan 1 1995

    Fingerprint

    Testis
    Rats
    Messenger RNA
    Spermatocytes
    Spermatogenesis
    Genes

    Keywords

    • Gene expression
    • Isozyme switching
    • Lactate dehydrogenase
    • Ldh-c, Ldh-a
    • Puberty
    • Spermatogenesis
    • Translational regulation

    ASJC Scopus subject areas

    • Biochemistry
    • Physiology

    Cite this

    Expression profile of Ldh-a in the developing rat Rattus norvegicus testis suggests regulation at the translational level. / Salehi-Ashtiani, Kourosh; Goldberg, Erwin.

    In: Comparative Biochemistry and Physiology -- Part B: Biochemistry and, Vol. 110, No. 3, 01.01.1995, p. 623-627.

    Research output: Contribution to journalArticle

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