Expression of mesoderm markers in Xenopus laevis Keller explants

Jean-Pierre Saint-Jeannet, A. A. Karavanov, I. B. Dawid

Research output: Contribution to journalArticle

Abstract

In an attempt to document at the molecular level the behavior of mesodermal cells in Keller explant preparation, we have analyzed the time course of expression of four molecular markers of mesoderm gsc, Xbra, Xnot and XLIM-1. Our findings demonstrate that, (i) all mesodermal markers tested were expressed in the explants, but patterning of the mesoderm appeared incomplete; (ii) during convergence and extension of the explants, mesodermal cells did not invade the ectodermal tissue at any time tested, supporting the view that mesoderm establishes exclusively planar contacts with the ectoderm in this preparation; (iii) planar contacts were not sufficient to promote the neural expression of XLIM-1 protein in these explants.

Original languageEnglish (US)
Pages (from-to)605-611
Number of pages7
JournalInternational Journal of Developmental Biology
Volume38
Issue number4
StatePublished - 1994

Fingerprint

Xenopus laevis
Mesoderm
Ectoderm
Proteins

Keywords

  • Amphibia
  • Mesoderm
  • Neural induction
  • Regionalization

ASJC Scopus subject areas

  • Cell Biology
  • Developmental Biology

Cite this

Expression of mesoderm markers in Xenopus laevis Keller explants. / Saint-Jeannet, Jean-Pierre; Karavanov, A. A.; Dawid, I. B.

In: International Journal of Developmental Biology, Vol. 38, No. 4, 1994, p. 605-611.

Research output: Contribution to journalArticle

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