Expedient synthesis of (±)-bipinnatin J

Paul A. Roethle, Dirk Trauner

Research output: Contribution to journalArticle

Abstract

A nine-step, stereoselective synthesis of bipinnatin J is described, which features a ruthenium-catalyzed Alder-ene reaction, a Stille cross coupling, and an intramolecular Nozaki-Hiyama-Kishi allylation as key steps. The biosynthetic relationship between bipinnatin J and complex polycyclic diterpenes isolated from gorgonian corals is discussed.

Original languageEnglish (US)
Pages (from-to)345-347
Number of pages3
JournalOrganic Letters
Volume8
Issue number2
DOIs
StatePublished - Jan 19 2006

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ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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