Examination of the association of sex and race/ethnicity with appearance concerns

A Scleroderma Patient-centered Intervention Network (SPIN) Cohort study

Lisa R. Jewett, Linda Kwakkenbos, Marie Eve Carrier, Vanessa L. Malcarne, Susan J. Bartlett, Daniel E. Furst, Karen Gottesman, Maureen D. Mayes, Shervin Assassi, Diana Harcourt, Heidi Williamson, Sindhu R. Johnson, Annett Körner, Virginia Steen, Rina S. Fox, Shadi Gholizadeh, Sarah D. Mills, Jacqueline C. Molnar, Danielle B. Rice, Brett D. Thombs & 31 others Murray Baron, Frank van den Hoogen, Dinesh Khanna, Luc Mouthon, Warren R. Nielson, Serge Poiraudeau, Robert Riggs, Maureen Sauve, Fredrick Wigley, Isabelle Boutron, Angela Costa Maia, Ghassan El-Baalbaki, Carolyn Ells, Cornelia van den Ende, Kim Fligelstone, Catherine Fortune, Tracy Frech, Dominique Godard, Daphna Harel, Marie Hudson, Ann Impens, Yeona Jang, Ann Tyrell Kennedy, Maggie Larche, Catarina Leite, Carlo Marra, Karen Nielsen, Janet L. Poole, Janet Pope, Alexandra Portales, SPIN Investigators

Research output: Contribution to journalArticle

Abstract

Objective. Appearance concerns are common in systemic sclerosis (SSc) and have been linked to younger age and more severe disease. No study has examined their association with sex or race/ethnicity. Methods. SSc patients were sampled from the Scleroderma Patient-centered Intervention Network Cohort. Presence of appearance concerns was assessed with a single item, and medical and sociodemographic information were collected. Results. Of 644 patients, appearance concerns were present in 72%, including 421 of 565 women (75%), 42 of 79 men (53%), 392 of 550 patients who identified as White (71%), 35 of 41 who identified as Black (85%), and 36 of 53 who identified as another race/ethnicity (68%). In multivariate analysis, women had significantly greater odds of reporting appearance concerns than men (odds ratio (OR)=2.97, 95% confidence interval (CI)=1.78-4.95, p < 0.001). Black patients had significantly greater odds of appearance concerns than White patients in unadjusted (OR=2.64, 95% CI=1.01-6.34, p=0.030), but not multivariate analysis (OR=1.76, 95% CI=0.67-4.60, p=0.250). Compared to a general population sample, appearance concerns were substantially more common in SSc, particularly for men across all age groups and for younger women. The most commonly reported features of concern were related to the face and head, followed by the hands and fingers; this did not differ by sex or race/ethnicity. Conclusion. Appearance concerns were common in SSc. Women were substantially more likely than men to have appearance concerns. Although nonsignificant in multivariate analysis, Black patients were more likely to have concerns than White patients, likely due to more severe changes in appearance.

Original languageEnglish (US)
Pages (from-to)92-99
Number of pages8
JournalClinical and Experimental Rheumatology
Volume34
StatePublished - 2016

Fingerprint

Cohort Studies
Systemic Scleroderma
Multivariate Analysis
Odds Ratio
Confidence Intervals
Fingers
Hand
Age Groups
Head
Population

Keywords

  • Appearance concerns
  • Race/ethnicity
  • Sex
  • Systemic sclerosis

ASJC Scopus subject areas

  • Immunology and Allergy
  • Rheumatology
  • Immunology

Cite this

Jewett, L. R., Kwakkenbos, L., Carrier, M. E., Malcarne, V. L., Bartlett, S. J., Furst, D. E., ... SPIN Investigators (2016). Examination of the association of sex and race/ethnicity with appearance concerns: A Scleroderma Patient-centered Intervention Network (SPIN) Cohort study. Clinical and Experimental Rheumatology, 34, 92-99.

Examination of the association of sex and race/ethnicity with appearance concerns : A Scleroderma Patient-centered Intervention Network (SPIN) Cohort study. / Jewett, Lisa R.; Kwakkenbos, Linda; Carrier, Marie Eve; Malcarne, Vanessa L.; Bartlett, Susan J.; Furst, Daniel E.; Gottesman, Karen; Mayes, Maureen D.; Assassi, Shervin; Harcourt, Diana; Williamson, Heidi; Johnson, Sindhu R.; Körner, Annett; Steen, Virginia; Fox, Rina S.; Gholizadeh, Shadi; Mills, Sarah D.; Molnar, Jacqueline C.; Rice, Danielle B.; Thombs, Brett D.; Baron, Murray; van den Hoogen, Frank; Khanna, Dinesh; Mouthon, Luc; Nielson, Warren R.; Poiraudeau, Serge; Riggs, Robert; Sauve, Maureen; Wigley, Fredrick; Boutron, Isabelle; Maia, Angela Costa; El-Baalbaki, Ghassan; Ells, Carolyn; van den Ende, Cornelia; Fligelstone, Kim; Fortune, Catherine; Frech, Tracy; Godard, Dominique; Harel, Daphna; Hudson, Marie; Impens, Ann; Jang, Yeona; Kennedy, Ann Tyrell; Larche, Maggie; Leite, Catarina; Marra, Carlo; Nielsen, Karen; Poole, Janet L.; Pope, Janet; Portales, Alexandra; SPIN Investigators.

In: Clinical and Experimental Rheumatology, Vol. 34, 2016, p. 92-99.

Research output: Contribution to journalArticle

Jewett, LR, Kwakkenbos, L, Carrier, ME, Malcarne, VL, Bartlett, SJ, Furst, DE, Gottesman, K, Mayes, MD, Assassi, S, Harcourt, D, Williamson, H, Johnson, SR, Körner, A, Steen, V, Fox, RS, Gholizadeh, S, Mills, SD, Molnar, JC, Rice, DB, Thombs, BD, Baron, M, van den Hoogen, F, Khanna, D, Mouthon, L, Nielson, WR, Poiraudeau, S, Riggs, R, Sauve, M, Wigley, F, Boutron, I, Maia, AC, El-Baalbaki, G, Ells, C, van den Ende, C, Fligelstone, K, Fortune, C, Frech, T, Godard, D, Harel, D, Hudson, M, Impens, A, Jang, Y, Kennedy, AT, Larche, M, Leite, C, Marra, C, Nielsen, K, Poole, JL, Pope, J, Portales, A & SPIN Investigators 2016, 'Examination of the association of sex and race/ethnicity with appearance concerns: A Scleroderma Patient-centered Intervention Network (SPIN) Cohort study', Clinical and Experimental Rheumatology, vol. 34, pp. 92-99.
Jewett, Lisa R. ; Kwakkenbos, Linda ; Carrier, Marie Eve ; Malcarne, Vanessa L. ; Bartlett, Susan J. ; Furst, Daniel E. ; Gottesman, Karen ; Mayes, Maureen D. ; Assassi, Shervin ; Harcourt, Diana ; Williamson, Heidi ; Johnson, Sindhu R. ; Körner, Annett ; Steen, Virginia ; Fox, Rina S. ; Gholizadeh, Shadi ; Mills, Sarah D. ; Molnar, Jacqueline C. ; Rice, Danielle B. ; Thombs, Brett D. ; Baron, Murray ; van den Hoogen, Frank ; Khanna, Dinesh ; Mouthon, Luc ; Nielson, Warren R. ; Poiraudeau, Serge ; Riggs, Robert ; Sauve, Maureen ; Wigley, Fredrick ; Boutron, Isabelle ; Maia, Angela Costa ; El-Baalbaki, Ghassan ; Ells, Carolyn ; van den Ende, Cornelia ; Fligelstone, Kim ; Fortune, Catherine ; Frech, Tracy ; Godard, Dominique ; Harel, Daphna ; Hudson, Marie ; Impens, Ann ; Jang, Yeona ; Kennedy, Ann Tyrell ; Larche, Maggie ; Leite, Catarina ; Marra, Carlo ; Nielsen, Karen ; Poole, Janet L. ; Pope, Janet ; Portales, Alexandra ; SPIN Investigators. / Examination of the association of sex and race/ethnicity with appearance concerns : A Scleroderma Patient-centered Intervention Network (SPIN) Cohort study. In: Clinical and Experimental Rheumatology. 2016 ; Vol. 34. pp. 92-99.
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title = "Examination of the association of sex and race/ethnicity with appearance concerns: A Scleroderma Patient-centered Intervention Network (SPIN) Cohort study",
abstract = "Objective. Appearance concerns are common in systemic sclerosis (SSc) and have been linked to younger age and more severe disease. No study has examined their association with sex or race/ethnicity. Methods. SSc patients were sampled from the Scleroderma Patient-centered Intervention Network Cohort. Presence of appearance concerns was assessed with a single item, and medical and sociodemographic information were collected. Results. Of 644 patients, appearance concerns were present in 72{\%}, including 421 of 565 women (75{\%}), 42 of 79 men (53{\%}), 392 of 550 patients who identified as White (71{\%}), 35 of 41 who identified as Black (85{\%}), and 36 of 53 who identified as another race/ethnicity (68{\%}). In multivariate analysis, women had significantly greater odds of reporting appearance concerns than men (odds ratio (OR)=2.97, 95{\%} confidence interval (CI)=1.78-4.95, p < 0.001). Black patients had significantly greater odds of appearance concerns than White patients in unadjusted (OR=2.64, 95{\%} CI=1.01-6.34, p=0.030), but not multivariate analysis (OR=1.76, 95{\%} CI=0.67-4.60, p=0.250). Compared to a general population sample, appearance concerns were substantially more common in SSc, particularly for men across all age groups and for younger women. The most commonly reported features of concern were related to the face and head, followed by the hands and fingers; this did not differ by sex or race/ethnicity. Conclusion. Appearance concerns were common in SSc. Women were substantially more likely than men to have appearance concerns. Although nonsignificant in multivariate analysis, Black patients were more likely to have concerns than White patients, likely due to more severe changes in appearance.",
keywords = "Appearance concerns, Race/ethnicity, Sex, Systemic sclerosis",
author = "Jewett, {Lisa R.} and Linda Kwakkenbos and Carrier, {Marie Eve} and Malcarne, {Vanessa L.} and Bartlett, {Susan J.} and Furst, {Daniel E.} and Karen Gottesman and Mayes, {Maureen D.} and Shervin Assassi and Diana Harcourt and Heidi Williamson and Johnson, {Sindhu R.} and Annett K{\"o}rner and Virginia Steen and Fox, {Rina S.} and Shadi Gholizadeh and Mills, {Sarah D.} and Molnar, {Jacqueline C.} and Rice, {Danielle B.} and Thombs, {Brett D.} and Murray Baron and {van den Hoogen}, Frank and Dinesh Khanna and Luc Mouthon and Nielson, {Warren R.} and Serge Poiraudeau and Robert Riggs and Maureen Sauve and Fredrick Wigley and Isabelle Boutron and Maia, {Angela Costa} and Ghassan El-Baalbaki and Carolyn Ells and {van den Ende}, Cornelia and Kim Fligelstone and Catherine Fortune and Tracy Frech and Dominique Godard and Daphna Harel and Marie Hudson and Ann Impens and Yeona Jang and Kennedy, {Ann Tyrell} and Maggie Larche and Catarina Leite and Carlo Marra and Karen Nielsen and Poole, {Janet L.} and Janet Pope and Alexandra Portales and {SPIN Investigators}",
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language = "English (US)",
volume = "34",
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journal = "Clinical and Experimental Rheumatology",
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TY - JOUR

T1 - Examination of the association of sex and race/ethnicity with appearance concerns

T2 - A Scleroderma Patient-centered Intervention Network (SPIN) Cohort study

AU - Jewett, Lisa R.

AU - Kwakkenbos, Linda

AU - Carrier, Marie Eve

AU - Malcarne, Vanessa L.

AU - Bartlett, Susan J.

AU - Furst, Daniel E.

AU - Gottesman, Karen

AU - Mayes, Maureen D.

AU - Assassi, Shervin

AU - Harcourt, Diana

AU - Williamson, Heidi

AU - Johnson, Sindhu R.

AU - Körner, Annett

AU - Steen, Virginia

AU - Fox, Rina S.

AU - Gholizadeh, Shadi

AU - Mills, Sarah D.

AU - Molnar, Jacqueline C.

AU - Rice, Danielle B.

AU - Thombs, Brett D.

AU - Baron, Murray

AU - van den Hoogen, Frank

AU - Khanna, Dinesh

AU - Mouthon, Luc

AU - Nielson, Warren R.

AU - Poiraudeau, Serge

AU - Riggs, Robert

AU - Sauve, Maureen

AU - Wigley, Fredrick

AU - Boutron, Isabelle

AU - Maia, Angela Costa

AU - El-Baalbaki, Ghassan

AU - Ells, Carolyn

AU - van den Ende, Cornelia

AU - Fligelstone, Kim

AU - Fortune, Catherine

AU - Frech, Tracy

AU - Godard, Dominique

AU - Harel, Daphna

AU - Hudson, Marie

AU - Impens, Ann

AU - Jang, Yeona

AU - Kennedy, Ann Tyrell

AU - Larche, Maggie

AU - Leite, Catarina

AU - Marra, Carlo

AU - Nielsen, Karen

AU - Poole, Janet L.

AU - Pope, Janet

AU - Portales, Alexandra

AU - SPIN Investigators

PY - 2016

Y1 - 2016

N2 - Objective. Appearance concerns are common in systemic sclerosis (SSc) and have been linked to younger age and more severe disease. No study has examined their association with sex or race/ethnicity. Methods. SSc patients were sampled from the Scleroderma Patient-centered Intervention Network Cohort. Presence of appearance concerns was assessed with a single item, and medical and sociodemographic information were collected. Results. Of 644 patients, appearance concerns were present in 72%, including 421 of 565 women (75%), 42 of 79 men (53%), 392 of 550 patients who identified as White (71%), 35 of 41 who identified as Black (85%), and 36 of 53 who identified as another race/ethnicity (68%). In multivariate analysis, women had significantly greater odds of reporting appearance concerns than men (odds ratio (OR)=2.97, 95% confidence interval (CI)=1.78-4.95, p < 0.001). Black patients had significantly greater odds of appearance concerns than White patients in unadjusted (OR=2.64, 95% CI=1.01-6.34, p=0.030), but not multivariate analysis (OR=1.76, 95% CI=0.67-4.60, p=0.250). Compared to a general population sample, appearance concerns were substantially more common in SSc, particularly for men across all age groups and for younger women. The most commonly reported features of concern were related to the face and head, followed by the hands and fingers; this did not differ by sex or race/ethnicity. Conclusion. Appearance concerns were common in SSc. Women were substantially more likely than men to have appearance concerns. Although nonsignificant in multivariate analysis, Black patients were more likely to have concerns than White patients, likely due to more severe changes in appearance.

AB - Objective. Appearance concerns are common in systemic sclerosis (SSc) and have been linked to younger age and more severe disease. No study has examined their association with sex or race/ethnicity. Methods. SSc patients were sampled from the Scleroderma Patient-centered Intervention Network Cohort. Presence of appearance concerns was assessed with a single item, and medical and sociodemographic information were collected. Results. Of 644 patients, appearance concerns were present in 72%, including 421 of 565 women (75%), 42 of 79 men (53%), 392 of 550 patients who identified as White (71%), 35 of 41 who identified as Black (85%), and 36 of 53 who identified as another race/ethnicity (68%). In multivariate analysis, women had significantly greater odds of reporting appearance concerns than men (odds ratio (OR)=2.97, 95% confidence interval (CI)=1.78-4.95, p < 0.001). Black patients had significantly greater odds of appearance concerns than White patients in unadjusted (OR=2.64, 95% CI=1.01-6.34, p=0.030), but not multivariate analysis (OR=1.76, 95% CI=0.67-4.60, p=0.250). Compared to a general population sample, appearance concerns were substantially more common in SSc, particularly for men across all age groups and for younger women. The most commonly reported features of concern were related to the face and head, followed by the hands and fingers; this did not differ by sex or race/ethnicity. Conclusion. Appearance concerns were common in SSc. Women were substantially more likely than men to have appearance concerns. Although nonsignificant in multivariate analysis, Black patients were more likely to have concerns than White patients, likely due to more severe changes in appearance.

KW - Appearance concerns

KW - Race/ethnicity

KW - Sex

KW - Systemic sclerosis

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