Evo-devo models of tooth development and the origin of hominoid molar diversity

Alejandra Ortiz, Shara Bailey, Gary T. Schwartz, Jean Jacques Hublin, Matthew M. Skinner

    Research output: Contribution to journalArticle

    Abstract

    The detailed anatomical features that characterize fossil hominin molars figure prominently in the reconstruction of their taxonomy, phylogeny, and paleobiology. Despite the prominence of molar form in human origins research, the underlying developmental mechanisms generating the diversity of tooth crown features remain poorly understood. A model of tooth morphogenesis-the patterning cascade model (PCM)-provides a developmental framework to explore how and why the varying molar morphologies arose throughout human evolution. We generated virtual maps of the inner enamel epithelium-an indelibly preserved record of enamel knot arrangement-in 17 living and fossil hominoid species to investigate whether the PCM explains the expression of all major accessory cusps. We found that most of the variation and evolutionary changes in hominoid molar morphology followed the general developmental rule shared by all mammals, outlined by the PCM. Our results have implications for the accurate interpretation of molar crown configuration in hominoid systematics.

    Original languageEnglish (US)
    Article numbereaar2334
    JournalScience advances
    Volume4
    Issue number4
    DOIs
    StatePublished - Apr 11 2018

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    Fossils
    Dental Enamel
    Tooth
    Tooth Crown
    Hominidae
    Phylogeny
    Crowns
    Morphogenesis
    Mammals
    Epithelium
    Research

    ASJC Scopus subject areas

    • General

    Cite this

    Ortiz, A., Bailey, S., Schwartz, G. T., Hublin, J. J., & Skinner, M. M. (2018). Evo-devo models of tooth development and the origin of hominoid molar diversity. Science advances, 4(4), [eaar2334]. https://doi.org/10.1126/sciadv.aar2334

    Evo-devo models of tooth development and the origin of hominoid molar diversity. / Ortiz, Alejandra; Bailey, Shara; Schwartz, Gary T.; Hublin, Jean Jacques; Skinner, Matthew M.

    In: Science advances, Vol. 4, No. 4, eaar2334, 11.04.2018.

    Research output: Contribution to journalArticle

    Ortiz, A, Bailey, S, Schwartz, GT, Hublin, JJ & Skinner, MM 2018, 'Evo-devo models of tooth development and the origin of hominoid molar diversity', Science advances, vol. 4, no. 4, eaar2334. https://doi.org/10.1126/sciadv.aar2334
    Ortiz, Alejandra ; Bailey, Shara ; Schwartz, Gary T. ; Hublin, Jean Jacques ; Skinner, Matthew M. / Evo-devo models of tooth development and the origin of hominoid molar diversity. In: Science advances. 2018 ; Vol. 4, No. 4.
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