Evidence for working memory storage operations in perceptual cortex

Kartik Sreenivasan, Caterina Gratton, Jason Vytlacil, Mark D'Esposito

Research output: Contribution to journalArticle

Abstract

Isolating the short-term storage component of working memory (WM) from the myriad of associated executive processes has been an enduring challenge. Recent efforts have identified patterns of activity in visual regions that contain information about items being held in WM. However, it remains unclear (1) whether these representations withstand intervening sensory input and (2) how communication between multimodal association cortex and the unimodal perceptual regions supporting WM representations is involved in WM storage. We present evidence that the features of a face held in WM are stored within face-processing regions, that these representations persist across subsequent sensory input, and that information about the match between sensory input and a memory representation is relayed forward from perceptual to prefrontal regions. Participants were presented with a series of probe faces and indicated whether each probe matched a target face held in WM. We parametrically varied the feature similarity between the probe and target faces. Activity within face-processing regions scaled linearly with the degree of feature similarity between the probe face and the features of the target face, suggesting that the features of the target face were stored in these regions. Furthermore, directed connectivity measures revealed that the direction of information flow that was optimal for performance was from sensory regions that stored the features of the target face to dorsal prefrontal regions, supporting the notion that sensory input is compared to representations stored within perceptual regions and is subsequently relayed forward. Together, these findings indicate that WM storage operations are carried out within perceptual cortex.

Original languageEnglish (US)
Pages (from-to)117-128
Number of pages12
JournalCognitive, Affective and Behavioral Neuroscience
Volume14
Issue number1
DOIs
StatePublished - Jan 1 2014

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Short-Term Memory
Communication

Keywords

  • Functional connectivity
  • Working memory

ASJC Scopus subject areas

  • Cognitive Neuroscience
  • Behavioral Neuroscience

Cite this

Evidence for working memory storage operations in perceptual cortex. / Sreenivasan, Kartik; Gratton, Caterina; Vytlacil, Jason; D'Esposito, Mark.

In: Cognitive, Affective and Behavioral Neuroscience, Vol. 14, No. 1, 01.01.2014, p. 117-128.

Research output: Contribution to journalArticle

Sreenivasan, Kartik ; Gratton, Caterina ; Vytlacil, Jason ; D'Esposito, Mark. / Evidence for working memory storage operations in perceptual cortex. In: Cognitive, Affective and Behavioral Neuroscience. 2014 ; Vol. 14, No. 1. pp. 117-128.
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