Evaluation of collagen-based membranes for guided bone regeneration, by three-dimensional computerized microtomography

Paulo Coelho, Gabriela Giro, Wanki Kim, Rodrigo Granato, Charles Marin, Estevam Augusto Bonfante, Samara Bonfante, Thomas Lilin, Marcelo Suzuki

Research output: Contribution to journalArticle

Abstract

Objective: The aim of this study was to evaluate the use of a collagen-based membrane compared with no treatment on guided bone regeneration by 3-dimensional computerized microtomography (μCT). Study Design: Defects were created between the mesial and distal premolar roots of the second and third premolars (beagle dogs; n = 8). A collagen-based membrane (Vitala; Osteogenics Biomedical Inc., TX, USA) was placed in one of the defects (membrane group; n = 16), and the other was left untreated (no-membrane group; n = 16). Left and right sides provided healing samples for 2 and 16 weeks. Three-dimensional bone architecture was acquired by μCT and categorized as fully regenerated (F, bone height and width) or nonregenerated (N). Results: Chi-square tests (95% level of significance) showed that tooth did not have an effect on outcome (P =.5). Significantly higher F outcomes were observed at 16 weeks than 2 weeks (P =.008) and in membrane group than in no-membrane group (P =.008). Conclusions: The collagen-based membrane influenced bone regeneration at the furcation.

Original languageEnglish (US)
Pages (from-to)437-443
Number of pages7
JournalOral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Volume114
Issue number4
DOIs
StatePublished - Oct 2012

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Bone Regeneration
Collagen
Membranes
Bicuspid
Bone and Bones
Chi-Square Distribution
Tooth
Dogs

ASJC Scopus subject areas

  • Surgery
  • Oral Surgery
  • Pathology and Forensic Medicine
  • Radiology Nuclear Medicine and imaging
  • Dentistry (miscellaneous)

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Evaluation of collagen-based membranes for guided bone regeneration, by three-dimensional computerized microtomography. / Coelho, Paulo; Giro, Gabriela; Kim, Wanki; Granato, Rodrigo; Marin, Charles; Bonfante, Estevam Augusto; Bonfante, Samara; Lilin, Thomas; Suzuki, Marcelo.

In: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Vol. 114, No. 4, 10.2012, p. 437-443.

Research output: Contribution to journalArticle

Coelho, Paulo ; Giro, Gabriela ; Kim, Wanki ; Granato, Rodrigo ; Marin, Charles ; Bonfante, Estevam Augusto ; Bonfante, Samara ; Lilin, Thomas ; Suzuki, Marcelo. / Evaluation of collagen-based membranes for guided bone regeneration, by three-dimensional computerized microtomography. In: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 2012 ; Vol. 114, No. 4. pp. 437-443.
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