Enzymatic desymmetrization of a centrosymmetric diacetate

C. Böhm, W. F. Austin, D. Trauner

Research output: Contribution to journalArticle


An enantiomerically pure cyclohexanol was synthesized starting from para-xylene 1. The key steps are a stereoselective twofold hydroboration and a pig liver esterase (PLE)-catalyzed desymmetrization of the centrosymmetric cyclohexanediacetate 4.

Original languageEnglish (US)
Pages (from-to)71-74
Number of pages4
JournalTetrahedron Asymmetry
Issue number1
StatePublished - Jan 6 2003


ASJC Scopus subject areas

  • Catalysis
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

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