Enhanced ratiometric fluorescent indicators for magnesium based on azoles of the heavier chalcogens

Mohammad S. Afzal, Jean Philippe Pitteloud, Daniela Buccella

Research output: Contribution to journalArticle

Abstract

Red-shifted fluorescent indicators for magnesium were developed by incorporation of sulfur or selenium in the azole moiety of 'fura' fluorophores. Single atom replacement in the acceptor of these ITC probes affords longer excitation and emission wavelengths as well as greater separation between excitation bands, valuable for ratiometric intracellular Mg<sup>2+</sup> imaging.

Original languageEnglish (US)
Pages (from-to)11358-11361
Number of pages4
JournalChemical Communications
Volume50
Issue number77
DOIs
StatePublished - 2014

Fingerprint

Chalcogens
Azoles
Fluorophores
Selenium
Sulfur
Magnesium
Imaging techniques
Wavelength
Atoms

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis
  • Ceramics and Composites
  • Electronic, Optical and Magnetic Materials
  • Surfaces, Coatings and Films
  • Materials Chemistry
  • Metals and Alloys
  • Medicine(all)

Cite this

Enhanced ratiometric fluorescent indicators for magnesium based on azoles of the heavier chalcogens. / Afzal, Mohammad S.; Pitteloud, Jean Philippe; Buccella, Daniela.

In: Chemical Communications, Vol. 50, No. 77, 2014, p. 11358-11361.

Research output: Contribution to journalArticle

Afzal, Mohammad S. ; Pitteloud, Jean Philippe ; Buccella, Daniela. / Enhanced ratiometric fluorescent indicators for magnesium based on azoles of the heavier chalcogens. In: Chemical Communications. 2014 ; Vol. 50, No. 77. pp. 11358-11361.
@article{ed0a7b15d6054639aa1fad1ccf4a80f8,
title = "Enhanced ratiometric fluorescent indicators for magnesium based on azoles of the heavier chalcogens",
abstract = "Red-shifted fluorescent indicators for magnesium were developed by incorporation of sulfur or selenium in the azole moiety of 'fura' fluorophores. Single atom replacement in the acceptor of these ITC probes affords longer excitation and emission wavelengths as well as greater separation between excitation bands, valuable for ratiometric intracellular Mg2+ imaging.",
author = "Afzal, {Mohammad S.} and Pitteloud, {Jean Philippe} and Daniela Buccella",
year = "2014",
doi = "10.1039/c4cc04460f",
language = "English (US)",
volume = "50",
pages = "11358--11361",
journal = "Chemical Communications",
issn = "1359-7345",
publisher = "Royal Society of Chemistry",
number = "77",

}

TY - JOUR

T1 - Enhanced ratiometric fluorescent indicators for magnesium based on azoles of the heavier chalcogens

AU - Afzal, Mohammad S.

AU - Pitteloud, Jean Philippe

AU - Buccella, Daniela

PY - 2014

Y1 - 2014

N2 - Red-shifted fluorescent indicators for magnesium were developed by incorporation of sulfur or selenium in the azole moiety of 'fura' fluorophores. Single atom replacement in the acceptor of these ITC probes affords longer excitation and emission wavelengths as well as greater separation between excitation bands, valuable for ratiometric intracellular Mg2+ imaging.

AB - Red-shifted fluorescent indicators for magnesium were developed by incorporation of sulfur or selenium in the azole moiety of 'fura' fluorophores. Single atom replacement in the acceptor of these ITC probes affords longer excitation and emission wavelengths as well as greater separation between excitation bands, valuable for ratiometric intracellular Mg2+ imaging.

UR - http://www.scopus.com/inward/record.url?scp=84907073971&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84907073971&partnerID=8YFLogxK

U2 - 10.1039/c4cc04460f

DO - 10.1039/c4cc04460f

M3 - Article

VL - 50

SP - 11358

EP - 11361

JO - Chemical Communications

JF - Chemical Communications

SN - 1359-7345

IS - 77

ER -