Enhanced Intersubject Correlations during Movie Viewing Correlate with Successful Episodic Encoding

Uri Hasson, Orit Furman, Dav Clark, Yadin Dudai, Lila Davachi

Research output: Contribution to journalArticle

Abstract

While much has been learned regarding the neural substrates supporting episodic encoding using highly controlled experimental protocols, relatively little is known regarding the neural bases of episodic encoding of real-world events. In an effort to examine this issue, we measured fMRI activity while observers viewed a novel TV sitcom. Three weeks later, subsequent memory (SM) for the narrative content of movie events was assessed. We analyzed the encoding data for intersubject correlations (ISC) based on subjects' subsequent memory (ISC-SM) performance to identify brain regions whose BOLD response is significantly more correlated across subjects during portions of the movie that are successfully as compared to unsuccessfully encoded. These regions include the parahippocampal gyrus, superior temporal gyrus, anterior temporal poles, and the temporal-parietal junction. Further analyses reveal (1) that these correlated regions can display distinct activation profiles and (2) that the results seen with the ISC-SM analysis are complementary to more traditional linear models and allow analysis of complex time course data. Thus, the ISC-SM analysis extends traditional subsequent memory findings to a rich, dynamic and more ecologically valid situation.

Original languageEnglish (US)
Pages (from-to)452-462
Number of pages11
JournalNeuron
Volume57
Issue number3
DOIs
StatePublished - Feb 7 2008

Fingerprint

Motion Pictures
Parahippocampal Gyrus
Temporal Lobe
Linear Models
Magnetic Resonance Imaging
Brain

Keywords

  • SYSNEURO

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Enhanced Intersubject Correlations during Movie Viewing Correlate with Successful Episodic Encoding. / Hasson, Uri; Furman, Orit; Clark, Dav; Dudai, Yadin; Davachi, Lila.

In: Neuron, Vol. 57, No. 3, 07.02.2008, p. 452-462.

Research output: Contribution to journalArticle

Hasson, Uri ; Furman, Orit ; Clark, Dav ; Dudai, Yadin ; Davachi, Lila. / Enhanced Intersubject Correlations during Movie Viewing Correlate with Successful Episodic Encoding. In: Neuron. 2008 ; Vol. 57, No. 3. pp. 452-462.
@article{bcb5fb565c1341eea0545dcbec77e6c3,
title = "Enhanced Intersubject Correlations during Movie Viewing Correlate with Successful Episodic Encoding",
abstract = "While much has been learned regarding the neural substrates supporting episodic encoding using highly controlled experimental protocols, relatively little is known regarding the neural bases of episodic encoding of real-world events. In an effort to examine this issue, we measured fMRI activity while observers viewed a novel TV sitcom. Three weeks later, subsequent memory (SM) for the narrative content of movie events was assessed. We analyzed the encoding data for intersubject correlations (ISC) based on subjects' subsequent memory (ISC-SM) performance to identify brain regions whose BOLD response is significantly more correlated across subjects during portions of the movie that are successfully as compared to unsuccessfully encoded. These regions include the parahippocampal gyrus, superior temporal gyrus, anterior temporal poles, and the temporal-parietal junction. Further analyses reveal (1) that these correlated regions can display distinct activation profiles and (2) that the results seen with the ISC-SM analysis are complementary to more traditional linear models and allow analysis of complex time course data. Thus, the ISC-SM analysis extends traditional subsequent memory findings to a rich, dynamic and more ecologically valid situation.",
keywords = "SYSNEURO",
author = "Uri Hasson and Orit Furman and Dav Clark and Yadin Dudai and Lila Davachi",
year = "2008",
month = "2",
day = "7",
doi = "10.1016/j.neuron.2007.12.009",
language = "English (US)",
volume = "57",
pages = "452--462",
journal = "Neuron",
issn = "0896-6273",
publisher = "Cell Press",
number = "3",

}

TY - JOUR

T1 - Enhanced Intersubject Correlations during Movie Viewing Correlate with Successful Episodic Encoding

AU - Hasson, Uri

AU - Furman, Orit

AU - Clark, Dav

AU - Dudai, Yadin

AU - Davachi, Lila

PY - 2008/2/7

Y1 - 2008/2/7

N2 - While much has been learned regarding the neural substrates supporting episodic encoding using highly controlled experimental protocols, relatively little is known regarding the neural bases of episodic encoding of real-world events. In an effort to examine this issue, we measured fMRI activity while observers viewed a novel TV sitcom. Three weeks later, subsequent memory (SM) for the narrative content of movie events was assessed. We analyzed the encoding data for intersubject correlations (ISC) based on subjects' subsequent memory (ISC-SM) performance to identify brain regions whose BOLD response is significantly more correlated across subjects during portions of the movie that are successfully as compared to unsuccessfully encoded. These regions include the parahippocampal gyrus, superior temporal gyrus, anterior temporal poles, and the temporal-parietal junction. Further analyses reveal (1) that these correlated regions can display distinct activation profiles and (2) that the results seen with the ISC-SM analysis are complementary to more traditional linear models and allow analysis of complex time course data. Thus, the ISC-SM analysis extends traditional subsequent memory findings to a rich, dynamic and more ecologically valid situation.

AB - While much has been learned regarding the neural substrates supporting episodic encoding using highly controlled experimental protocols, relatively little is known regarding the neural bases of episodic encoding of real-world events. In an effort to examine this issue, we measured fMRI activity while observers viewed a novel TV sitcom. Three weeks later, subsequent memory (SM) for the narrative content of movie events was assessed. We analyzed the encoding data for intersubject correlations (ISC) based on subjects' subsequent memory (ISC-SM) performance to identify brain regions whose BOLD response is significantly more correlated across subjects during portions of the movie that are successfully as compared to unsuccessfully encoded. These regions include the parahippocampal gyrus, superior temporal gyrus, anterior temporal poles, and the temporal-parietal junction. Further analyses reveal (1) that these correlated regions can display distinct activation profiles and (2) that the results seen with the ISC-SM analysis are complementary to more traditional linear models and allow analysis of complex time course data. Thus, the ISC-SM analysis extends traditional subsequent memory findings to a rich, dynamic and more ecologically valid situation.

KW - SYSNEURO

UR - http://www.scopus.com/inward/record.url?scp=37549010543&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=37549010543&partnerID=8YFLogxK

U2 - 10.1016/j.neuron.2007.12.009

DO - 10.1016/j.neuron.2007.12.009

M3 - Article

VL - 57

SP - 452

EP - 462

JO - Neuron

JF - Neuron

SN - 0896-6273

IS - 3

ER -