Enhanced Brain Correlations during Rest Are Related to Memory for Recent Experiences

Arielle Tambini, Nicholas Ketz, Lila Davachi

Research output: Contribution to journalArticle

Abstract

Long-term storage of episodic memories is hypothesized to result from the off-line transfer of information from the hippocampus to neocortex, allowing a hippocampal-independent cortical representation to emerge. However, off-line hippocampal-cortical interactions have not been demonstrated to be linked with long-term memory. Here, using functional magnetic resonance imaging, we examined if hippocampal-cortical BOLD correlations during rest following an associative encoding task are related to later associative memory performance. Our data show enhanced functional connectivity between the hippocampus and a portion of the lateral occipital complex (LO) during rest following a task with high subsequent memory compared to pretask baseline resting connectivity. This effect is not seen during rest following a task with poor subsequent memory. Furthermore, the magnitude of hippocampal-LO correlations during posttask rest predicts individual differences in later associative memory. These results demonstrate the importance of postexperience resting brain correlations for memory for recent experiences. Video Abstract: {An electronic component is presented}.

Original languageEnglish (US)
Pages (from-to)280-290
Number of pages11
JournalNeuron
Volume65
Issue number2
DOIs
StatePublished - Jan 28 2010

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Brain
Hippocampus
Episodic Memory
Long-Term Memory
Neocortex
Individuality
Magnetic Resonance Imaging
Transfer (Psychology)

Keywords

  • SYSNEURO

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Enhanced Brain Correlations during Rest Are Related to Memory for Recent Experiences. / Tambini, Arielle; Ketz, Nicholas; Davachi, Lila.

In: Neuron, Vol. 65, No. 2, 28.01.2010, p. 280-290.

Research output: Contribution to journalArticle

Tambini, Arielle ; Ketz, Nicholas ; Davachi, Lila. / Enhanced Brain Correlations during Rest Are Related to Memory for Recent Experiences. In: Neuron. 2010 ; Vol. 65, No. 2. pp. 280-290.
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