Electrostatic interactions in cations and their importance in biology and chemistry

Deborah M. Smith, Keith Woerpel

Research output: Contribution to journalArticle

Abstract

Electrostatic effects exert strongly stabilizing influences on cations, in many cases controlling the conformational preferences of these cations. The lowest energy conformers are ones where the positive charge is brought closest to substituents bearing partial negative charges. These conformational biases, along with stereoelectronic effects, can control the stereoselectivity of reactions involving carbocationic intermediates.

Original languageEnglish (US)
Pages (from-to)1195-1201
Number of pages7
JournalOrganic and Biomolecular Chemistry
Volume4
Issue number7
DOIs
StatePublished - 2006

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Coulomb interactions
Static Electricity
biology
Cations
Bearings (structural)
chemistry
electrostatics
cations
Stereoselectivity
Electrostatics
interactions
energy

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Chemistry(all)

Cite this

Electrostatic interactions in cations and their importance in biology and chemistry. / Smith, Deborah M.; Woerpel, Keith.

In: Organic and Biomolecular Chemistry, Vol. 4, No. 7, 2006, p. 1195-1201.

Research output: Contribution to journalArticle

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