Efficacy of sexually transmitted disease/human immunodeficiency virus sexual risk-reduction intervention for African American adolescent females seeking sexual health services: A randomized controlled trial

Ralph DiClemente, Gina M. Wingood, Eve S. Rose, Jessica M. Sales, Delia L. Lang, Angela M. Caliendo, James W. Hardin, Richard A. Crosby

Research output: Contribution to journalArticle

Abstract

Objectives: To evaluate the efficacy of an intervention to reduce incident sexually transmitted disease (STD) and enhance STD/human immunodeficiency virus (HIV)-preventive behaviors and psychosocial mediators. Design: A randomized controlled trial of an HIV prevention program. Setting: Clinic-based sample in Atlanta, Georgia. Participants: African American adolescent females (N=715), aged 15 to 21 years, seeking sexual health services. Participants completed an audio computerassisted self-interview and provided self-collected vaginal specimens for STD testing. Intervention: Intervention participants received two 4-hour group sessions and 4 telephone contacts over a 12-month period, targeting personal, relational, sociocultural, and structural factors associated with adolescents' STD/HIV risk, and were given vouchers facilitating male partners' STD testing/treatment. Main Outcome Measure: Incident chlamydial infections. Results: Over the 12-month follow-up, fewer adolescents in the intervention had a chlamydial infection (42 vs 67; risk ratio [RR], 0.65; 95% confidence interval [CI], 0.42 to 0.98; P=.04) or recurrent chlamydial infection (4 vs 14; RR, 0.25; 95% CI, 0.08 to 0.83; P=.02). Adolescents in the intervention also reported a higher proportion of condom-protected sex acts in the 60 days preceding follow-up assessments (mean difference, 10.84; 95% CI, 5.27 to 16.42; P<.001) and less frequent douching (mean difference, -0.76; 95% CI, -1.15 to -0.37; P=.001). Adolescents in the intervention were also more likely to report consistent condom use in the 60 days preceding follow-up assessments (RR, 1. 41; 95% CI, 1.09 to 1.80; P=.01) and condom use at last intercourse (RR, 1.30; 95% CI, 1.09 to 1.54; P=.005). Intervention effects were observed for psychosocial mediators of STD/HIV-preventive behaviors. Conclusion: Interventions for African American adolescent females can reduce chlamydial infections and enhance STD/HIV-preventive behaviors and psychosocial mediators of STD/HIV-preventive behaviors. Trial Registration: clinicaltrials.gov Identifier: NCT00633906.

Original languageEnglish (US)
Pages (from-to)1112-1121
Number of pages10
JournalArchives of Pediatrics and Adolescent Medicine
Volume163
Issue number12
DOIs
StatePublished - Dec 1 2009

Fingerprint

Reproductive Health
Risk Reduction Behavior
Sexually Transmitted Diseases
African Americans
Health Services
Randomized Controlled Trials
HIV
Confidence Intervals
Condoms
Odds Ratio
Infection
Safe Sex
Therapeutic Irrigation
Telephone
Outcome Assessment (Health Care)
Interviews

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Efficacy of sexually transmitted disease/human immunodeficiency virus sexual risk-reduction intervention for African American adolescent females seeking sexual health services : A randomized controlled trial. / DiClemente, Ralph; Wingood, Gina M.; Rose, Eve S.; Sales, Jessica M.; Lang, Delia L.; Caliendo, Angela M.; Hardin, James W.; Crosby, Richard A.

In: Archives of Pediatrics and Adolescent Medicine, Vol. 163, No. 12, 01.12.2009, p. 1112-1121.

Research output: Contribution to journalArticle

DiClemente, Ralph ; Wingood, Gina M. ; Rose, Eve S. ; Sales, Jessica M. ; Lang, Delia L. ; Caliendo, Angela M. ; Hardin, James W. ; Crosby, Richard A. / Efficacy of sexually transmitted disease/human immunodeficiency virus sexual risk-reduction intervention for African American adolescent females seeking sexual health services : A randomized controlled trial. In: Archives of Pediatrics and Adolescent Medicine. 2009 ; Vol. 163, No. 12. pp. 1112-1121.
@article{5132e9c090bb4573a778e0ec2fab0435,
title = "Efficacy of sexually transmitted disease/human immunodeficiency virus sexual risk-reduction intervention for African American adolescent females seeking sexual health services: A randomized controlled trial",
abstract = "Objectives: To evaluate the efficacy of an intervention to reduce incident sexually transmitted disease (STD) and enhance STD/human immunodeficiency virus (HIV)-preventive behaviors and psychosocial mediators. Design: A randomized controlled trial of an HIV prevention program. Setting: Clinic-based sample in Atlanta, Georgia. Participants: African American adolescent females (N=715), aged 15 to 21 years, seeking sexual health services. Participants completed an audio computerassisted self-interview and provided self-collected vaginal specimens for STD testing. Intervention: Intervention participants received two 4-hour group sessions and 4 telephone contacts over a 12-month period, targeting personal, relational, sociocultural, and structural factors associated with adolescents' STD/HIV risk, and were given vouchers facilitating male partners' STD testing/treatment. Main Outcome Measure: Incident chlamydial infections. Results: Over the 12-month follow-up, fewer adolescents in the intervention had a chlamydial infection (42 vs 67; risk ratio [RR], 0.65; 95{\%} confidence interval [CI], 0.42 to 0.98; P=.04) or recurrent chlamydial infection (4 vs 14; RR, 0.25; 95{\%} CI, 0.08 to 0.83; P=.02). Adolescents in the intervention also reported a higher proportion of condom-protected sex acts in the 60 days preceding follow-up assessments (mean difference, 10.84; 95{\%} CI, 5.27 to 16.42; P<.001) and less frequent douching (mean difference, -0.76; 95{\%} CI, -1.15 to -0.37; P=.001). Adolescents in the intervention were also more likely to report consistent condom use in the 60 days preceding follow-up assessments (RR, 1. 41; 95{\%} CI, 1.09 to 1.80; P=.01) and condom use at last intercourse (RR, 1.30; 95{\%} CI, 1.09 to 1.54; P=.005). Intervention effects were observed for psychosocial mediators of STD/HIV-preventive behaviors. Conclusion: Interventions for African American adolescent females can reduce chlamydial infections and enhance STD/HIV-preventive behaviors and psychosocial mediators of STD/HIV-preventive behaviors. Trial Registration: clinicaltrials.gov Identifier: NCT00633906.",
author = "Ralph DiClemente and Wingood, {Gina M.} and Rose, {Eve S.} and Sales, {Jessica M.} and Lang, {Delia L.} and Caliendo, {Angela M.} and Hardin, {James W.} and Crosby, {Richard A.}",
year = "2009",
month = "12",
day = "1",
doi = "10.1001/archpediatrics.2009.205",
language = "English (US)",
volume = "163",
pages = "1112--1121",
journal = "JAMA Pediatrics",
issn = "2168-6203",
publisher = "American Medical Association",
number = "12",

}

TY - JOUR

T1 - Efficacy of sexually transmitted disease/human immunodeficiency virus sexual risk-reduction intervention for African American adolescent females seeking sexual health services

T2 - A randomized controlled trial

AU - DiClemente, Ralph

AU - Wingood, Gina M.

AU - Rose, Eve S.

AU - Sales, Jessica M.

AU - Lang, Delia L.

AU - Caliendo, Angela M.

AU - Hardin, James W.

AU - Crosby, Richard A.

PY - 2009/12/1

Y1 - 2009/12/1

N2 - Objectives: To evaluate the efficacy of an intervention to reduce incident sexually transmitted disease (STD) and enhance STD/human immunodeficiency virus (HIV)-preventive behaviors and psychosocial mediators. Design: A randomized controlled trial of an HIV prevention program. Setting: Clinic-based sample in Atlanta, Georgia. Participants: African American adolescent females (N=715), aged 15 to 21 years, seeking sexual health services. Participants completed an audio computerassisted self-interview and provided self-collected vaginal specimens for STD testing. Intervention: Intervention participants received two 4-hour group sessions and 4 telephone contacts over a 12-month period, targeting personal, relational, sociocultural, and structural factors associated with adolescents' STD/HIV risk, and were given vouchers facilitating male partners' STD testing/treatment. Main Outcome Measure: Incident chlamydial infections. Results: Over the 12-month follow-up, fewer adolescents in the intervention had a chlamydial infection (42 vs 67; risk ratio [RR], 0.65; 95% confidence interval [CI], 0.42 to 0.98; P=.04) or recurrent chlamydial infection (4 vs 14; RR, 0.25; 95% CI, 0.08 to 0.83; P=.02). Adolescents in the intervention also reported a higher proportion of condom-protected sex acts in the 60 days preceding follow-up assessments (mean difference, 10.84; 95% CI, 5.27 to 16.42; P<.001) and less frequent douching (mean difference, -0.76; 95% CI, -1.15 to -0.37; P=.001). Adolescents in the intervention were also more likely to report consistent condom use in the 60 days preceding follow-up assessments (RR, 1. 41; 95% CI, 1.09 to 1.80; P=.01) and condom use at last intercourse (RR, 1.30; 95% CI, 1.09 to 1.54; P=.005). Intervention effects were observed for psychosocial mediators of STD/HIV-preventive behaviors. Conclusion: Interventions for African American adolescent females can reduce chlamydial infections and enhance STD/HIV-preventive behaviors and psychosocial mediators of STD/HIV-preventive behaviors. Trial Registration: clinicaltrials.gov Identifier: NCT00633906.

AB - Objectives: To evaluate the efficacy of an intervention to reduce incident sexually transmitted disease (STD) and enhance STD/human immunodeficiency virus (HIV)-preventive behaviors and psychosocial mediators. Design: A randomized controlled trial of an HIV prevention program. Setting: Clinic-based sample in Atlanta, Georgia. Participants: African American adolescent females (N=715), aged 15 to 21 years, seeking sexual health services. Participants completed an audio computerassisted self-interview and provided self-collected vaginal specimens for STD testing. Intervention: Intervention participants received two 4-hour group sessions and 4 telephone contacts over a 12-month period, targeting personal, relational, sociocultural, and structural factors associated with adolescents' STD/HIV risk, and were given vouchers facilitating male partners' STD testing/treatment. Main Outcome Measure: Incident chlamydial infections. Results: Over the 12-month follow-up, fewer adolescents in the intervention had a chlamydial infection (42 vs 67; risk ratio [RR], 0.65; 95% confidence interval [CI], 0.42 to 0.98; P=.04) or recurrent chlamydial infection (4 vs 14; RR, 0.25; 95% CI, 0.08 to 0.83; P=.02). Adolescents in the intervention also reported a higher proportion of condom-protected sex acts in the 60 days preceding follow-up assessments (mean difference, 10.84; 95% CI, 5.27 to 16.42; P<.001) and less frequent douching (mean difference, -0.76; 95% CI, -1.15 to -0.37; P=.001). Adolescents in the intervention were also more likely to report consistent condom use in the 60 days preceding follow-up assessments (RR, 1. 41; 95% CI, 1.09 to 1.80; P=.01) and condom use at last intercourse (RR, 1.30; 95% CI, 1.09 to 1.54; P=.005). Intervention effects were observed for psychosocial mediators of STD/HIV-preventive behaviors. Conclusion: Interventions for African American adolescent females can reduce chlamydial infections and enhance STD/HIV-preventive behaviors and psychosocial mediators of STD/HIV-preventive behaviors. Trial Registration: clinicaltrials.gov Identifier: NCT00633906.

UR - http://www.scopus.com/inward/record.url?scp=71549163772&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=71549163772&partnerID=8YFLogxK

U2 - 10.1001/archpediatrics.2009.205

DO - 10.1001/archpediatrics.2009.205

M3 - Article

VL - 163

SP - 1112

EP - 1121

JO - JAMA Pediatrics

JF - JAMA Pediatrics

SN - 2168-6203

IS - 12

ER -