Effectiveness of influenza vaccine for the prevention of asthma exacerbations

C. Christy, C. A. Aligne, P. Auinger, T. Pulcino, Michael Weitzman

    Research output: Contribution to journalArticle

    Abstract

    Background: There is a lack of clinical evidence that annual vaccination against influenza prevents asthma exacerbations in children. Methods: Retrospective cohort study of 800 children with asthma, where one half did, and the other half did not receive the influenza vaccine. The two groups were compared with respect to clinic visits, emergency department (ED) visits, and hospitalisations for asthma. In multivariable analyses, adjustment was made for baseline asthma severity, prior utilisation of health services, receipt of vaccine in the previous year, and demographic variables. Results: After adjusting for other variables, the vaccine group had a significantly increased risk of asthma related clinic visits and ED visits (odds ratios 3.4 and 1.9, respectively). Conclusion: This study failed to provide evidence that the influenza vaccine prevents paediatric asthma exacerbations.

    Original languageEnglish (US)
    Pages (from-to)734-735
    Number of pages2
    JournalArchives of Disease in Childhood
    Volume89
    Issue number8
    DOIs
    StatePublished - Aug 1 2004

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    Influenza Vaccines
    Asthma
    Ambulatory Care
    Hospital Emergency Service
    Vaccines
    Human Influenza
    Health Services
    Vaccination
    Hospitalization
    Cohort Studies
    Retrospective Studies
    Odds Ratio
    Demography
    Pediatrics

    ASJC Scopus subject areas

    • Pediatrics, Perinatology, and Child Health

    Cite this

    Effectiveness of influenza vaccine for the prevention of asthma exacerbations. / Christy, C.; Aligne, C. A.; Auinger, P.; Pulcino, T.; Weitzman, Michael.

    In: Archives of Disease in Childhood, Vol. 89, No. 8, 01.08.2004, p. 734-735.

    Research output: Contribution to journalArticle

    Christy, C, Aligne, CA, Auinger, P, Pulcino, T & Weitzman, M 2004, 'Effectiveness of influenza vaccine for the prevention of asthma exacerbations', Archives of Disease in Childhood, vol. 89, no. 8, pp. 734-735. https://doi.org/10.1136/adc.2003.030999
    Christy, C. ; Aligne, C. A. ; Auinger, P. ; Pulcino, T. ; Weitzman, Michael. / Effectiveness of influenza vaccine for the prevention of asthma exacerbations. In: Archives of Disease in Childhood. 2004 ; Vol. 89, No. 8. pp. 734-735.
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