Effectiveness of influenza vaccine for the prevention of asthma exacerbations

C. Christy, C. A. Aligne, P. Auinger, T. Pulcino, Michael Weitzman

Research output: Contribution to journalArticle

Abstract

Background: There is a lack of clinical evidence that annual vaccination against influenza prevents asthma exacerbations in children. Methods: Retrospective cohort study of 800 children with asthma, where one half did, and the other half did not receive the influenza vaccine. The two groups were compared with respect to clinic visits, emergency department (ED) visits, and hospitalisations for asthma. In multivariable analyses, adjustment was made for baseline asthma severity, prior utilisation of health services, receipt of vaccine in the previous year, and demographic variables. Results: After adjusting for other variables, the vaccine group had a significantly increased risk of asthma related clinic visits and ED visits (odds ratios 3.4 and 1.9, respectively). Conclusion: This study failed to provide evidence that the influenza vaccine prevents paediatric asthma exacerbations.

Original languageEnglish (US)
Pages (from-to)734-735
Number of pages2
JournalArchives of Disease in Childhood
Volume89
Issue number8
DOIs
StatePublished - Aug 1 2004

Fingerprint

Influenza Vaccines
Asthma
Ambulatory Care
Hospital Emergency Service
Vaccines
Human Influenza
Health Services
Vaccination
Hospitalization
Cohort Studies
Retrospective Studies
Odds Ratio
Demography
Pediatrics

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Effectiveness of influenza vaccine for the prevention of asthma exacerbations. / Christy, C.; Aligne, C. A.; Auinger, P.; Pulcino, T.; Weitzman, Michael.

In: Archives of Disease in Childhood, Vol. 89, No. 8, 01.08.2004, p. 734-735.

Research output: Contribution to journalArticle

Christy, C. ; Aligne, C. A. ; Auinger, P. ; Pulcino, T. ; Weitzman, Michael. / Effectiveness of influenza vaccine for the prevention of asthma exacerbations. In: Archives of Disease in Childhood. 2004 ; Vol. 89, No. 8. pp. 734-735.
@article{717846e479f7422dba637e29710bd65e,
title = "Effectiveness of influenza vaccine for the prevention of asthma exacerbations",
abstract = "Background: There is a lack of clinical evidence that annual vaccination against influenza prevents asthma exacerbations in children. Methods: Retrospective cohort study of 800 children with asthma, where one half did, and the other half did not receive the influenza vaccine. The two groups were compared with respect to clinic visits, emergency department (ED) visits, and hospitalisations for asthma. In multivariable analyses, adjustment was made for baseline asthma severity, prior utilisation of health services, receipt of vaccine in the previous year, and demographic variables. Results: After adjusting for other variables, the vaccine group had a significantly increased risk of asthma related clinic visits and ED visits (odds ratios 3.4 and 1.9, respectively). Conclusion: This study failed to provide evidence that the influenza vaccine prevents paediatric asthma exacerbations.",
author = "C. Christy and Aligne, {C. A.} and P. Auinger and T. Pulcino and Michael Weitzman",
year = "2004",
month = "8",
day = "1",
doi = "10.1136/adc.2003.030999",
language = "English (US)",
volume = "89",
pages = "734--735",
journal = "Archives of Disease in Childhood",
issn = "0003-9888",
publisher = "BMJ Publishing Group",
number = "8",

}

TY - JOUR

T1 - Effectiveness of influenza vaccine for the prevention of asthma exacerbations

AU - Christy, C.

AU - Aligne, C. A.

AU - Auinger, P.

AU - Pulcino, T.

AU - Weitzman, Michael

PY - 2004/8/1

Y1 - 2004/8/1

N2 - Background: There is a lack of clinical evidence that annual vaccination against influenza prevents asthma exacerbations in children. Methods: Retrospective cohort study of 800 children with asthma, where one half did, and the other half did not receive the influenza vaccine. The two groups were compared with respect to clinic visits, emergency department (ED) visits, and hospitalisations for asthma. In multivariable analyses, adjustment was made for baseline asthma severity, prior utilisation of health services, receipt of vaccine in the previous year, and demographic variables. Results: After adjusting for other variables, the vaccine group had a significantly increased risk of asthma related clinic visits and ED visits (odds ratios 3.4 and 1.9, respectively). Conclusion: This study failed to provide evidence that the influenza vaccine prevents paediatric asthma exacerbations.

AB - Background: There is a lack of clinical evidence that annual vaccination against influenza prevents asthma exacerbations in children. Methods: Retrospective cohort study of 800 children with asthma, where one half did, and the other half did not receive the influenza vaccine. The two groups were compared with respect to clinic visits, emergency department (ED) visits, and hospitalisations for asthma. In multivariable analyses, adjustment was made for baseline asthma severity, prior utilisation of health services, receipt of vaccine in the previous year, and demographic variables. Results: After adjusting for other variables, the vaccine group had a significantly increased risk of asthma related clinic visits and ED visits (odds ratios 3.4 and 1.9, respectively). Conclusion: This study failed to provide evidence that the influenza vaccine prevents paediatric asthma exacerbations.

UR - http://www.scopus.com/inward/record.url?scp=3242892358&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=3242892358&partnerID=8YFLogxK

U2 - 10.1136/adc.2003.030999

DO - 10.1136/adc.2003.030999

M3 - Article

C2 - 15269071

AN - SCOPUS:3242892358

VL - 89

SP - 734

EP - 735

JO - Archives of Disease in Childhood

JF - Archives of Disease in Childhood

SN - 0003-9888

IS - 8

ER -