Effect of Surface Modifications on Early Bone Healing Around Plateau Root Form Implants: An Experimental Study in Rabbits

Marcelo Suzuki, Monica D. Calasans-Maia, Charles Marin, Rodrigo Granato, Jose N. Gil, Jose M. Granjeiro, Paulo Coelho

Research output: Contribution to journalArticle

Abstract

Purpose: The objective of the present study was to evaluate the biomechanical fixation and bone-to-implant contact (BIC) of plateau root form implants of varied surfaces. Materials and Methods: Plateau root form implants, 3.5 mm in diameter, 8 mm in length, with 4 surfaces (n = 16 each)-machined, alumina-blasted/acid-etched, alumina-blasted/acid-etched plus nanothickness bioceramic coating, and plasma-sprayed calcium-phosphate-were used. They were bilaterally placed at the distal femur of 16 New Zealand rabbits and remained in place for 2 and 4 weeks in vivo. After euthanizing the rabbits, the implants were subjected to torque to interface fracture and were subsequently processed as nondecalcified ∼30-μm-thickness slides for histomorphologic analysis and BIC determination. Statistical analysis was performed using analysis of variance at the 95% level of significance, considering implantation time and implant surface as independent variables and the torque-to-interface fracture and BIC as dependent variables. Results: The torque-to-interface fracture was significantly affected by the implant surface (P < .001) but was not affected by the implantation time (P > .20). The implantation time and implant surface had significant effects on the BIC (P < .04 and P < .001, respectively). The greatest torque-to-interface fracture and BIC was observed for the plasma-sprayed calcium-phosphate. Conclusion: The implant surface significantly influenced early bone healing around plateau root form implants.

Original languageEnglish (US)
Pages (from-to)1631-1638
Number of pages8
JournalJournal of Oral and Maxillofacial Surgery
Volume68
Issue number7
DOIs
StatePublished - Jul 2010

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Experimental Implants
Torque
Rabbits
Bone and Bones
Aluminum Oxide
Bone Fractures
Acids
Femur
Analysis of Variance

ASJC Scopus subject areas

  • Oral Surgery
  • Otorhinolaryngology
  • Surgery

Cite this

Effect of Surface Modifications on Early Bone Healing Around Plateau Root Form Implants : An Experimental Study in Rabbits. / Suzuki, Marcelo; Calasans-Maia, Monica D.; Marin, Charles; Granato, Rodrigo; Gil, Jose N.; Granjeiro, Jose M.; Coelho, Paulo.

In: Journal of Oral and Maxillofacial Surgery, Vol. 68, No. 7, 07.2010, p. 1631-1638.

Research output: Contribution to journalArticle

Suzuki, Marcelo ; Calasans-Maia, Monica D. ; Marin, Charles ; Granato, Rodrigo ; Gil, Jose N. ; Granjeiro, Jose M. ; Coelho, Paulo. / Effect of Surface Modifications on Early Bone Healing Around Plateau Root Form Implants : An Experimental Study in Rabbits. In: Journal of Oral and Maxillofacial Surgery. 2010 ; Vol. 68, No. 7. pp. 1631-1638.
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abstract = "Purpose: The objective of the present study was to evaluate the biomechanical fixation and bone-to-implant contact (BIC) of plateau root form implants of varied surfaces. Materials and Methods: Plateau root form implants, 3.5 mm in diameter, 8 mm in length, with 4 surfaces (n = 16 each)-machined, alumina-blasted/acid-etched, alumina-blasted/acid-etched plus nanothickness bioceramic coating, and plasma-sprayed calcium-phosphate-were used. They were bilaterally placed at the distal femur of 16 New Zealand rabbits and remained in place for 2 and 4 weeks in vivo. After euthanizing the rabbits, the implants were subjected to torque to interface fracture and were subsequently processed as nondecalcified ∼30-μm-thickness slides for histomorphologic analysis and BIC determination. Statistical analysis was performed using analysis of variance at the 95{\%} level of significance, considering implantation time and implant surface as independent variables and the torque-to-interface fracture and BIC as dependent variables. Results: The torque-to-interface fracture was significantly affected by the implant surface (P < .001) but was not affected by the implantation time (P > .20). The implantation time and implant surface had significant effects on the BIC (P < .04 and P < .001, respectively). The greatest torque-to-interface fracture and BIC was observed for the plasma-sprayed calcium-phosphate. Conclusion: The implant surface significantly influenced early bone healing around plateau root form implants.",
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N2 - Purpose: The objective of the present study was to evaluate the biomechanical fixation and bone-to-implant contact (BIC) of plateau root form implants of varied surfaces. Materials and Methods: Plateau root form implants, 3.5 mm in diameter, 8 mm in length, with 4 surfaces (n = 16 each)-machined, alumina-blasted/acid-etched, alumina-blasted/acid-etched plus nanothickness bioceramic coating, and plasma-sprayed calcium-phosphate-were used. They were bilaterally placed at the distal femur of 16 New Zealand rabbits and remained in place for 2 and 4 weeks in vivo. After euthanizing the rabbits, the implants were subjected to torque to interface fracture and were subsequently processed as nondecalcified ∼30-μm-thickness slides for histomorphologic analysis and BIC determination. Statistical analysis was performed using analysis of variance at the 95% level of significance, considering implantation time and implant surface as independent variables and the torque-to-interface fracture and BIC as dependent variables. Results: The torque-to-interface fracture was significantly affected by the implant surface (P < .001) but was not affected by the implantation time (P > .20). The implantation time and implant surface had significant effects on the BIC (P < .04 and P < .001, respectively). The greatest torque-to-interface fracture and BIC was observed for the plasma-sprayed calcium-phosphate. Conclusion: The implant surface significantly influenced early bone healing around plateau root form implants.

AB - Purpose: The objective of the present study was to evaluate the biomechanical fixation and bone-to-implant contact (BIC) of plateau root form implants of varied surfaces. Materials and Methods: Plateau root form implants, 3.5 mm in diameter, 8 mm in length, with 4 surfaces (n = 16 each)-machined, alumina-blasted/acid-etched, alumina-blasted/acid-etched plus nanothickness bioceramic coating, and plasma-sprayed calcium-phosphate-were used. They were bilaterally placed at the distal femur of 16 New Zealand rabbits and remained in place for 2 and 4 weeks in vivo. After euthanizing the rabbits, the implants were subjected to torque to interface fracture and were subsequently processed as nondecalcified ∼30-μm-thickness slides for histomorphologic analysis and BIC determination. Statistical analysis was performed using analysis of variance at the 95% level of significance, considering implantation time and implant surface as independent variables and the torque-to-interface fracture and BIC as dependent variables. Results: The torque-to-interface fracture was significantly affected by the implant surface (P < .001) but was not affected by the implantation time (P > .20). The implantation time and implant surface had significant effects on the BIC (P < .04 and P < .001, respectively). The greatest torque-to-interface fracture and BIC was observed for the plasma-sprayed calcium-phosphate. Conclusion: The implant surface significantly influenced early bone healing around plateau root form implants.

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