Effect of Si addition on Ca- and P-impregnated implant surfaces with nanometer-scale roughness: An experimental study in dogs

Paulo Coelho, Rodrigo Granato, Charles Marin, Ryo Jimbo, Siyan Lin, Lukasz Witek, Marcelo Suzuki, Estevam A. Bonfante

Research output: Contribution to journalArticle

Abstract

Objectives: To investigate the effect of Si addition on a nanometer-scale roughness Ca and P implant surfaces in a canine tibia model by biomechanical and histomorphometric evaluations. Material and methods: The implant surfaces comprised a resorbable media CaP microblasted (control) and a CaP resorbable media+silica-boost microblasted (experimental) surfaces. Surfaces were characterized by scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), and optical interferometry (IFM) down to the nanometric level. The animal model involved the bilateral placement of control (n=24) and experimental surface (n=24) implants along the proximal tibiae of six dogs, remaining in vivo for 2 or 4 weeks. After euthanization, half of the specimens were torqued-to-interface failure, and the other half was subjected to histomorphologic and bone-to-implant contact (BIC) evaluation. Torque and BIC statistical evaluation was performed by the Friedman test at 95% level of significance, and comparisons between groups was performed by the Dunn test. Results: IFM and SEM observations depicted comparable roughness parameters for both implant surfaces on the micrometer and nanometer scales. XPS analysis revealed similar chemical composition, except for the addition of Si on the experimental group. Torque-to-interface failure and BIC mean values showed no significant differences (P=0.25 and 0.51, respectively) at both 2- and 4-week evaluation points for experimental and control groups. Early bone healing histomorphologic events were similar between groups. Conclusions: The experimental surface resulted in not significantly different biomechanical fixation and BIC relative to control. Both surfaces were biocompatible and osseoconductive.

Original languageEnglish (US)
Pages (from-to)373-378
Number of pages6
JournalClinical Oral Implants Research
Volume23
Issue number3
DOIs
StatePublished - Mar 2012

Fingerprint

Dogs
Bone and Bones
Interferometry
Photoelectron Spectroscopy
Torque
Tibia
Electron Scanning Microscopy
Silicon Dioxide
Canidae
Animal Models
Control Groups

Keywords

  • Animal study
  • Biomechanical
  • CaP
  • Implant surface
  • Nanometer

ASJC Scopus subject areas

  • Oral Surgery

Cite this

Effect of Si addition on Ca- and P-impregnated implant surfaces with nanometer-scale roughness : An experimental study in dogs. / Coelho, Paulo; Granato, Rodrigo; Marin, Charles; Jimbo, Ryo; Lin, Siyan; Witek, Lukasz; Suzuki, Marcelo; Bonfante, Estevam A.

In: Clinical Oral Implants Research, Vol. 23, No. 3, 03.2012, p. 373-378.

Research output: Contribution to journalArticle

Coelho, Paulo ; Granato, Rodrigo ; Marin, Charles ; Jimbo, Ryo ; Lin, Siyan ; Witek, Lukasz ; Suzuki, Marcelo ; Bonfante, Estevam A. / Effect of Si addition on Ca- and P-impregnated implant surfaces with nanometer-scale roughness : An experimental study in dogs. In: Clinical Oral Implants Research. 2012 ; Vol. 23, No. 3. pp. 373-378.
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abstract = "Objectives: To investigate the effect of Si addition on a nanometer-scale roughness Ca and P implant surfaces in a canine tibia model by biomechanical and histomorphometric evaluations. Material and methods: The implant surfaces comprised a resorbable media CaP microblasted (control) and a CaP resorbable media+silica-boost microblasted (experimental) surfaces. Surfaces were characterized by scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), and optical interferometry (IFM) down to the nanometric level. The animal model involved the bilateral placement of control (n=24) and experimental surface (n=24) implants along the proximal tibiae of six dogs, remaining in vivo for 2 or 4 weeks. After euthanization, half of the specimens were torqued-to-interface failure, and the other half was subjected to histomorphologic and bone-to-implant contact (BIC) evaluation. Torque and BIC statistical evaluation was performed by the Friedman test at 95{\%} level of significance, and comparisons between groups was performed by the Dunn test. Results: IFM and SEM observations depicted comparable roughness parameters for both implant surfaces on the micrometer and nanometer scales. XPS analysis revealed similar chemical composition, except for the addition of Si on the experimental group. Torque-to-interface failure and BIC mean values showed no significant differences (P=0.25 and 0.51, respectively) at both 2- and 4-week evaluation points for experimental and control groups. Early bone healing histomorphologic events were similar between groups. Conclusions: The experimental surface resulted in not significantly different biomechanical fixation and BIC relative to control. Both surfaces were biocompatible and osseoconductive.",
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