Effect of reversible cross-linker, N,N′-bis(acryloyl)cystamine, on calcium ion adsorption by imprinted gels

Haruyuki Hiratani, Carmen Alvarez-Lorenzo, Jeffrey Chuang, Orhan Guney, Alexander Yu Grosberg, Toyoichi Tanaka

    Research output: Contribution to journalArticle

    Abstract

    Imprinted gels incorporating two different breakable cross-linkers, a PbMAA2 complex and a disulfide (S-S) bond, were prepared by radical polymerization. After the lead ions were removed by washing, these gels showed a high affinity for calcium ions. Breakage and subsequent reconnection of the S-S bonds in the absence of Ca2+ decreases the Ca2+ binding affinity of the gel. This indicates that random reconnection of the S-S bonds produces a frustration in the adsorption of Ca2+ by the carboxyl groups. However, if the S-S bonds were reconnected in the presence of Ca2+ and the Ca2+ was subsequently removed (the post-imprinting technique), the resulting gels showed a higher binding affinity for Ca2+. This indicates that the post-imprinting technique creates a more favorable conformation for Ca2+ binding in the polymer network. We interpret our data to mean that "memory" of target-binding sites was encoded effectively into the polymer network by the initial imprinting technique and then enhanced by the post-imprinting technique.

    Original languageEnglish (US)
    Pages (from-to)4431-4436
    Number of pages6
    JournalLangmuir
    Volume17
    Issue number14
    DOIs
    StatePublished - Jul 10 2001

    Fingerprint

    Cystamine
    calcium
    Calcium
    Gels
    gels
    Ions
    affinity
    Adsorption
    adsorption
    Polymers
    ions
    washing
    polymers
    carboxyl group
    disulfides
    Binding sites
    frustration
    Free radical polymerization
    Washing
    Disulfides

    ASJC Scopus subject areas

    • Physical and Theoretical Chemistry
    • Colloid and Surface Chemistry

    Cite this

    Hiratani, H., Alvarez-Lorenzo, C., Chuang, J., Guney, O., Grosberg, A. Y., & Tanaka, T. (2001). Effect of reversible cross-linker, N,N′-bis(acryloyl)cystamine, on calcium ion adsorption by imprinted gels. Langmuir, 17(14), 4431-4436. https://doi.org/10.1021/la010056m

    Effect of reversible cross-linker, N,N′-bis(acryloyl)cystamine, on calcium ion adsorption by imprinted gels. / Hiratani, Haruyuki; Alvarez-Lorenzo, Carmen; Chuang, Jeffrey; Guney, Orhan; Grosberg, Alexander Yu; Tanaka, Toyoichi.

    In: Langmuir, Vol. 17, No. 14, 10.07.2001, p. 4431-4436.

    Research output: Contribution to journalArticle

    Hiratani, H, Alvarez-Lorenzo, C, Chuang, J, Guney, O, Grosberg, AY & Tanaka, T 2001, 'Effect of reversible cross-linker, N,N′-bis(acryloyl)cystamine, on calcium ion adsorption by imprinted gels', Langmuir, vol. 17, no. 14, pp. 4431-4436. https://doi.org/10.1021/la010056m
    Hiratani H, Alvarez-Lorenzo C, Chuang J, Guney O, Grosberg AY, Tanaka T. Effect of reversible cross-linker, N,N′-bis(acryloyl)cystamine, on calcium ion adsorption by imprinted gels. Langmuir. 2001 Jul 10;17(14):4431-4436. https://doi.org/10.1021/la010056m
    Hiratani, Haruyuki ; Alvarez-Lorenzo, Carmen ; Chuang, Jeffrey ; Guney, Orhan ; Grosberg, Alexander Yu ; Tanaka, Toyoichi. / Effect of reversible cross-linker, N,N′-bis(acryloyl)cystamine, on calcium ion adsorption by imprinted gels. In: Langmuir. 2001 ; Vol. 17, No. 14. pp. 4431-4436.
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