Early bone healing around implant surfaces treated with variations in the resorbable blasting media method. A study in rabbits

Ryan Jeong, Charles Marin, Rodrigo Granato, Marcelo Suzuki, Jose N. Gil, Jose M. Granjeiro, Paulo Coelho

Research output: Contribution to journalArticle

Abstract

Objective: this study aimed to histomorphologically and histomorphometrically evaluate the in vivo response to three variations in the resorbable blasting media (RBM) surface processing in a rabbit femur model. Study Design: screw root form implants with 3.75 mm in diameter by 8 mm in length presenting four surfaces (n=8 each): alumina-blasted/acid-etched (AB/AE), bioresorbable ceramic blasted (TCP), TCP + acid etching, and AB/AE + TCP were characterized by scanning electron microscopy (SEM) and atomic force microscopy (AFM). The implants were placed at the distal femur of 8 New Zeland rabbits, remaining for 2 weeks in vivo. After sacrifice, the implants were nondecalcified processed to 30 micro m thickness slides for histomorphology and bone-to-implant contact (BIC) determination. Statistical analysis was performed by one-way ANOVA at 95% level of significance considering implant surface as the independent variable and BIC as the dependent variable. Results: SEM and AFM showed that all surfaces presented rough textures and that calciu-hosohate particles were observed at the TCP group surface. Histologic evaluation showed intimate interaction between newly formed woven bone and all implant surfaces, demonstrating that all surfaces were biocompatible and osseoconductive. Significant differences in BIC were observed between the AB/AE and the AB/AE + TCP, and intermediate values observed for the TCP and TCP + Acid surfaces. Conclusion: irrespective of RBM processing variation, all surfaces were osseoconductive and biocaompatible. The differences in BIC between groups warrant further bone-implant interface biomechanical characterization.

Original languageEnglish (US)
JournalMedicina Oral, Patologia Oral y Cirugia Bucal
Volume15
Issue number1
DOIs
StatePublished - Jan 2010

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Aluminum Oxide
Rabbits
Bone and Bones
Acids
Atomic Force Microscopy
Electron Scanning Microscopy
Femur
Ceramics
Analysis of Variance

Keywords

  • Dental implant
  • In vivo
  • Resorbable blasting media
  • Surface treatment

ASJC Scopus subject areas

  • Dentistry(all)
  • Otorhinolaryngology
  • Surgery

Cite this

Early bone healing around implant surfaces treated with variations in the resorbable blasting media method. A study in rabbits. / Jeong, Ryan; Marin, Charles; Granato, Rodrigo; Suzuki, Marcelo; Gil, Jose N.; Granjeiro, Jose M.; Coelho, Paulo.

In: Medicina Oral, Patologia Oral y Cirugia Bucal, Vol. 15, No. 1, 01.2010.

Research output: Contribution to journalArticle

Jeong, Ryan ; Marin, Charles ; Granato, Rodrigo ; Suzuki, Marcelo ; Gil, Jose N. ; Granjeiro, Jose M. ; Coelho, Paulo. / Early bone healing around implant surfaces treated with variations in the resorbable blasting media method. A study in rabbits. In: Medicina Oral, Patologia Oral y Cirugia Bucal. 2010 ; Vol. 15, No. 1.
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abstract = "Objective: this study aimed to histomorphologically and histomorphometrically evaluate the in vivo response to three variations in the resorbable blasting media (RBM) surface processing in a rabbit femur model. Study Design: screw root form implants with 3.75 mm in diameter by 8 mm in length presenting four surfaces (n=8 each): alumina-blasted/acid-etched (AB/AE), bioresorbable ceramic blasted (TCP), TCP + acid etching, and AB/AE + TCP were characterized by scanning electron microscopy (SEM) and atomic force microscopy (AFM). The implants were placed at the distal femur of 8 New Zeland rabbits, remaining for 2 weeks in vivo. After sacrifice, the implants were nondecalcified processed to 30 micro m thickness slides for histomorphology and bone-to-implant contact (BIC) determination. Statistical analysis was performed by one-way ANOVA at 95{\%} level of significance considering implant surface as the independent variable and BIC as the dependent variable. Results: SEM and AFM showed that all surfaces presented rough textures and that calciu-hosohate particles were observed at the TCP group surface. Histologic evaluation showed intimate interaction between newly formed woven bone and all implant surfaces, demonstrating that all surfaces were biocompatible and osseoconductive. Significant differences in BIC were observed between the AB/AE and the AB/AE + TCP, and intermediate values observed for the TCP and TCP + Acid surfaces. Conclusion: irrespective of RBM processing variation, all surfaces were osseoconductive and biocaompatible. The differences in BIC between groups warrant further bone-implant interface biomechanical characterization.",
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