Dot by dot: Analyzing the glycome using lectin microarrays

João P. Ribeiro, Lara Mahal

Research output: Contribution to journalArticle

Abstract

The glycome, that is, the cohort of carbohydrates within a cell or tissue, plays a key part in diverse biological interactions involved in health and disease. Glycans are structurally complex and notoriously difficult to analyze. Lectin microarrays, a sensitive and high-throughput method for glycomic profiling, provide a global view of the glycome. In recent work, this technology has been successfully applied to a wide range of studies, from identification of glycan-based stem cell markers to the detection of pathogens and early diagnosis of disease. This review focuses on advances in the field of lectin microarrays.

Original languageEnglish (US)
Pages (from-to)827-831
Number of pages5
JournalCurrent Opinion in Chemical Biology
Volume17
Issue number5
DOIs
StatePublished - Oct 2013

Fingerprint

Microarrays
Lectins
Polysaccharides
Glycomics
Pathogens
Stem cells
Early Diagnosis
Stem Cells
Carbohydrates
Throughput
Health
Tissue
Technology

ASJC Scopus subject areas

  • Biochemistry
  • Analytical Chemistry

Cite this

Dot by dot : Analyzing the glycome using lectin microarrays. / Ribeiro, João P.; Mahal, Lara.

In: Current Opinion in Chemical Biology, Vol. 17, No. 5, 10.2013, p. 827-831.

Research output: Contribution to journalArticle

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