Dopamine pathway is highly diverged in primate species that differ markedly in social behavior

Christina M. Bergey, Jane E. Phillips-Conroy, Todd Disotell, Clifford J. Jolly

    Research output: Contribution to journalArticle

    Abstract

    In the endeavor to associate genetic variation with complex traits, closely related taxa are particularly fruitful for understanding the neurophysiological and genetic underpinnings of species-specific attributes. Similarity to humans has motivated research into nonhuman primate models, yet few studies of wild primates have investigated immediate causal factors of evolutionarily diverged social behaviors. Neurotransmitter differences have been invoked to explain the distinct behavioral suites of two baboon species in Awash, Ethiopia, which differ markedly in social behavior despite evolutionary propinquity. With this natural experiment, we test the hypothesis that genomic regions associated with monoamine neurotransmitters would be highly differentiated, and we identify a dopamine pathway as an outlier, highlighting the system as a potential cause of species-specific social behaviors. Dopamine levels and resultant variation in impulsivitywere likely under differential selection in the species due to social system structure differences, with either brash or circumspect social behavior advantageous to secure mating opportunities depending on the social backdrop. Such comparative studies into the causes of the behavioral agendas that create and interact with social systems are of particular interest, and differences in temperament related to boldness and associated with dopamine variation likely played important roles in the evolution of all social, behaviorally complex animals, including baboons and humans.

    Original languageEnglish (US)
    Pages (from-to)6178-6181
    Number of pages4
    JournalProceedings of the National Academy of Sciences of the United States of America
    Volume113
    Issue number22
    DOIs
    StatePublished - May 31 2016

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    Social Behavior
    Primates
    Dopamine
    Papio
    Neurotransmitter Agents
    Heartburn
    Ethiopia
    Temperament
    Research

    Keywords

    • Adaptive divergence
    • Baboon
    • Dopamine
    • Papio
    • Social behavior

    ASJC Scopus subject areas

    • General

    Cite this

    Dopamine pathway is highly diverged in primate species that differ markedly in social behavior. / Bergey, Christina M.; Phillips-Conroy, Jane E.; Disotell, Todd; Jolly, Clifford J.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, No. 22, 31.05.2016, p. 6178-6181.

    Research output: Contribution to journalArticle

    Bergey, Christina M. ; Phillips-Conroy, Jane E. ; Disotell, Todd ; Jolly, Clifford J. / Dopamine pathway is highly diverged in primate species that differ markedly in social behavior. In: Proceedings of the National Academy of Sciences of the United States of America. 2016 ; Vol. 113, No. 22. pp. 6178-6181.
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