Don't go chasing waterfalls excessive fluid resuscitation in severe sepsis and septic shock

Research output: Contribution to journalArticle


Aggressive fluid resuscitation is the mainstay therapy in modern sepsis management. Its efficacy was demonstrated in the landmark study by Emmanuel Rivers in 2001. However, more recent evidence largely shows that a positive fluid balance increases mortality in critically ill patients with sepsis. This article examines the theoretical benefits of fluid resuscitation and physiological responses to it that may negatively affect patients' outcome.

Original languageEnglish (US)
Pages (from-to)34-37
Number of pages4
JournalCritical care nursing quarterly
Issue number1
StatePublished - Jan 1 2016



  • Excessive fluid resuscitation
  • Sepsis
  • Septic shock
  • critically ill

ASJC Scopus subject areas

  • Critical Care

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