Don't go chasing waterfalls excessive fluid resuscitation in severe sepsis and septic shock

Research output: Contribution to journalArticle

Abstract

Aggressive fluid resuscitation is the mainstay therapy in modern sepsis management. Its efficacy was demonstrated in the landmark study by Emmanuel Rivers in 2001. However, more recent evidence largely shows that a positive fluid balance increases mortality in critically ill patients with sepsis. This article examines the theoretical benefits of fluid resuscitation and physiological responses to it that may negatively affect patients' outcome.

Original languageEnglish (US)
Pages (from-to)34-37
Number of pages4
JournalCritical Care Nursing Quarterly
Volume39
Issue number1
DOIs
StatePublished - Jan 1 2016

Fingerprint

Septic Shock
Resuscitation
Sepsis
Water-Electrolyte Balance
Rivers
Critical Illness
Mortality
Therapeutics

Keywords

  • critically ill
  • Excessive fluid resuscitation
  • Sepsis
  • Septic shock

ASJC Scopus subject areas

  • Critical Care

Cite this

Don't go chasing waterfalls excessive fluid resuscitation in severe sepsis and septic shock. / Chen, Leon.

In: Critical Care Nursing Quarterly, Vol. 39, No. 1, 01.01.2016, p. 34-37.

Research output: Contribution to journalArticle

@article{e0a7ff2079c84f68b254ebf5536274b7,
title = "Don't go chasing waterfalls excessive fluid resuscitation in severe sepsis and septic shock",
abstract = "Aggressive fluid resuscitation is the mainstay therapy in modern sepsis management. Its efficacy was demonstrated in the landmark study by Emmanuel Rivers in 2001. However, more recent evidence largely shows that a positive fluid balance increases mortality in critically ill patients with sepsis. This article examines the theoretical benefits of fluid resuscitation and physiological responses to it that may negatively affect patients' outcome.",
keywords = "critically ill, Excessive fluid resuscitation, Sepsis, Septic shock",
author = "Leon Chen",
year = "2016",
month = "1",
day = "1",
doi = "10.1097/CNQ.0000000000000094",
language = "English (US)",
volume = "39",
pages = "34--37",
journal = "Critical Care Nursing Quarterly",
issn = "0887-9303",
publisher = "Lippincott Williams and Wilkins",
number = "1",

}

TY - JOUR

T1 - Don't go chasing waterfalls excessive fluid resuscitation in severe sepsis and septic shock

AU - Chen, Leon

PY - 2016/1/1

Y1 - 2016/1/1

N2 - Aggressive fluid resuscitation is the mainstay therapy in modern sepsis management. Its efficacy was demonstrated in the landmark study by Emmanuel Rivers in 2001. However, more recent evidence largely shows that a positive fluid balance increases mortality in critically ill patients with sepsis. This article examines the theoretical benefits of fluid resuscitation and physiological responses to it that may negatively affect patients' outcome.

AB - Aggressive fluid resuscitation is the mainstay therapy in modern sepsis management. Its efficacy was demonstrated in the landmark study by Emmanuel Rivers in 2001. However, more recent evidence largely shows that a positive fluid balance increases mortality in critically ill patients with sepsis. This article examines the theoretical benefits of fluid resuscitation and physiological responses to it that may negatively affect patients' outcome.

KW - critically ill

KW - Excessive fluid resuscitation

KW - Sepsis

KW - Septic shock

UR - http://www.scopus.com/inward/record.url?scp=84952316071&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84952316071&partnerID=8YFLogxK

U2 - 10.1097/CNQ.0000000000000094

DO - 10.1097/CNQ.0000000000000094

M3 - Article

C2 - 26633156

AN - SCOPUS:84952316071

VL - 39

SP - 34

EP - 37

JO - Critical Care Nursing Quarterly

JF - Critical Care Nursing Quarterly

SN - 0887-9303

IS - 1

ER -