Do mitochondrial replacement techniques affect qualitative or numerical identity?

Research output: Contribution to journalArticle

Abstract

Mitochondrial replacement techniques (MRTs), known in the popular media as ’three-parent’ or ’three-person’ IVFs, have the potential to enable women with mitochondrial diseases to have children who are genetically related to them but without such diseases. In the debate regarding whether MRTs should be made available, an issue that has garnered considerable attention is whether MRTs affect the characteristics of an existing individual or whether they result in the creation of a new individual, given that MRTs involve the genetic manipulation of the germline. In other words, do MRTs affect the qualitative identity or the numerical identity of the resulting child? For instance, a group of panelists on behalf of the UK Human Fertilisation and Embryology Authority (HFEA) has claimed that MRTs affect only the qualitative identity of the resulting child, while the Working Group of the Nuffield Council on Bioethics (NCOB) has argued that MRTs would create a numerically distinct individual. In this article, I shall argue that MRTs do create a new and numerically distinct individual. Since my explanation is different from the NCOB’s explanation, I shall also offer reasons why my explanation is preferable to the NCOB’s explanation.

Original languageEnglish (US)
Pages (from-to)20-26
Number of pages7
JournalBioethics
Volume31
Issue number1
DOIs
StatePublished - Jan 1 2017

Fingerprint

Genetic Techniques
Mitochondrial Diseases
Bioethics
Embryology
Disease
Fertilization
working group
bioethics
manipulation
parents
human being
Replacement
Group

Keywords

  • Maternal spindle transfer
  • Mitochondrial donation
  • Mitochondrial replacement technique
  • Numerical identity
  • Personal identity
  • Qualitative identity
  • Three parent IVF

ASJC Scopus subject areas

  • Health(social science)
  • Philosophy
  • Health Policy

Cite this

Do mitochondrial replacement techniques affect qualitative or numerical identity? / Liao, S. Matthew.

In: Bioethics, Vol. 31, No. 1, 01.01.2017, p. 20-26.

Research output: Contribution to journalArticle

@article{9ebceec19def46649dea7c7413edd4d3,
title = "Do mitochondrial replacement techniques affect qualitative or numerical identity?",
abstract = "Mitochondrial replacement techniques (MRTs), known in the popular media as ’three-parent’ or ’three-person’ IVFs, have the potential to enable women with mitochondrial diseases to have children who are genetically related to them but without such diseases. In the debate regarding whether MRTs should be made available, an issue that has garnered considerable attention is whether MRTs affect the characteristics of an existing individual or whether they result in the creation of a new individual, given that MRTs involve the genetic manipulation of the germline. In other words, do MRTs affect the qualitative identity or the numerical identity of the resulting child? For instance, a group of panelists on behalf of the UK Human Fertilisation and Embryology Authority (HFEA) has claimed that MRTs affect only the qualitative identity of the resulting child, while the Working Group of the Nuffield Council on Bioethics (NCOB) has argued that MRTs would create a numerically distinct individual. In this article, I shall argue that MRTs do create a new and numerically distinct individual. Since my explanation is different from the NCOB’s explanation, I shall also offer reasons why my explanation is preferable to the NCOB’s explanation.",
keywords = "Maternal spindle transfer, Mitochondrial donation, Mitochondrial replacement technique, Numerical identity, Personal identity, Qualitative identity, Three parent IVF",
author = "Liao, {S. Matthew}",
year = "2017",
month = "1",
day = "1",
doi = "10.1111/bioe.12308",
language = "English (US)",
volume = "31",
pages = "20--26",
journal = "Bioethics",
issn = "0269-9702",
publisher = "Wiley-Blackwell",
number = "1",

}

TY - JOUR

T1 - Do mitochondrial replacement techniques affect qualitative or numerical identity?

AU - Liao, S. Matthew

PY - 2017/1/1

Y1 - 2017/1/1

N2 - Mitochondrial replacement techniques (MRTs), known in the popular media as ’three-parent’ or ’three-person’ IVFs, have the potential to enable women with mitochondrial diseases to have children who are genetically related to them but without such diseases. In the debate regarding whether MRTs should be made available, an issue that has garnered considerable attention is whether MRTs affect the characteristics of an existing individual or whether they result in the creation of a new individual, given that MRTs involve the genetic manipulation of the germline. In other words, do MRTs affect the qualitative identity or the numerical identity of the resulting child? For instance, a group of panelists on behalf of the UK Human Fertilisation and Embryology Authority (HFEA) has claimed that MRTs affect only the qualitative identity of the resulting child, while the Working Group of the Nuffield Council on Bioethics (NCOB) has argued that MRTs would create a numerically distinct individual. In this article, I shall argue that MRTs do create a new and numerically distinct individual. Since my explanation is different from the NCOB’s explanation, I shall also offer reasons why my explanation is preferable to the NCOB’s explanation.

AB - Mitochondrial replacement techniques (MRTs), known in the popular media as ’three-parent’ or ’three-person’ IVFs, have the potential to enable women with mitochondrial diseases to have children who are genetically related to them but without such diseases. In the debate regarding whether MRTs should be made available, an issue that has garnered considerable attention is whether MRTs affect the characteristics of an existing individual or whether they result in the creation of a new individual, given that MRTs involve the genetic manipulation of the germline. In other words, do MRTs affect the qualitative identity or the numerical identity of the resulting child? For instance, a group of panelists on behalf of the UK Human Fertilisation and Embryology Authority (HFEA) has claimed that MRTs affect only the qualitative identity of the resulting child, while the Working Group of the Nuffield Council on Bioethics (NCOB) has argued that MRTs would create a numerically distinct individual. In this article, I shall argue that MRTs do create a new and numerically distinct individual. Since my explanation is different from the NCOB’s explanation, I shall also offer reasons why my explanation is preferable to the NCOB’s explanation.

KW - Maternal spindle transfer

KW - Mitochondrial donation

KW - Mitochondrial replacement technique

KW - Numerical identity

KW - Personal identity

KW - Qualitative identity

KW - Three parent IVF

UR - http://www.scopus.com/inward/record.url?scp=85010867867&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85010867867&partnerID=8YFLogxK

U2 - 10.1111/bioe.12308

DO - 10.1111/bioe.12308

M3 - Article

C2 - 27973721

AN - SCOPUS:85010867867

VL - 31

SP - 20

EP - 26

JO - Bioethics

JF - Bioethics

SN - 0269-9702

IS - 1

ER -