DNA cruciforms

Neville R. Kallenbach, Min Zhong

Research output: Contribution to journalArticle

Abstract

Cruciforms represent a novel DNA state with unique physical and biological properties, including the ability to undergo branch migration in appropriate sequence backgrounds. Recent results establish a preferred geometry of immobile cruciforms in Mg2+ solution, the rate of branch migration, and the binding properties of cruciforms for proteins and small molecule ligands. A structure has been determined for three-arm branches with unpaired bases at the branch.

Original languageEnglish (US)
Pages (from-to)365-371
Number of pages7
JournalCurrent Opinion in Structural Biology
Volume4
Issue number3
DOIs
StatePublished - 1994

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Cruciform DNA
Ligands
DNA
Proteins

ASJC Scopus subject areas

  • Molecular Biology
  • Structural Biology

Cite this

DNA cruciforms. / Kallenbach, Neville R.; Zhong, Min.

In: Current Opinion in Structural Biology, Vol. 4, No. 3, 1994, p. 365-371.

Research output: Contribution to journalArticle

Kallenbach, NR & Zhong, M 1994, 'DNA cruciforms', Current Opinion in Structural Biology, vol. 4, no. 3, pp. 365-371. https://doi.org/10.1016/S0959-440X(94)90104-X
Kallenbach, Neville R. ; Zhong, Min. / DNA cruciforms. In: Current Opinion in Structural Biology. 1994 ; Vol. 4, No. 3. pp. 365-371.
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